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    Glossary Selenium Toxicity

    excessive selenium intake causing symptoms like hair loss and nail brittleness

    Selenium toxicity, also known as selenosis, occurs when there is an excessive accumulation of selenium in the body, often due to overconsumption of selenium-rich foods or supplements. Symptoms can include gastrointestinal distress, hair loss, nail brittleness, and in severe cases, neurological damage. It is important to maintain selenium intake within recommended limits to avoid these adverse effects.

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    1. Case Series Of Selenium Toxicity From A Nutritional Supplement Clinical toxicology · 2011 · 78 citations
    2. Selenium Toxicity: A Case of Selenosis Caused by a Nutritional Supplement Annals of Internal Medicine · 2008 · 71 citations
    3. Ingestion of a dietary supplement resulting in selenium toxicity Journal of the American Academy of Dermatology · 2010 · 27 citations
    4. Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: A review Journal of trace elements in medicine and biology · 2023 · 12 citations
    5. Selenium Toxicity in Domestic Animals 2021 · 4 citations
    6. Acute Selenium Toxicity Associated With a Dietary Supplement Archives of Internal Medicine · 2010 · 382 citations
    7. Systemic subchronic toxicity and comparison of four selenium nutritional supplements by 90-day oral exposure in Sprague-Dawley rats Food and chemical toxicology · 2023
    8. Lack of Toxicity of Selenium Sulfide Suspension for Hair Roots**From the Department of Dermatology, University of Pennsylvania, School of Medicine, Philadelphia, 4, Pennsylvania. Journal of Investigative Dermatology · 1962 · 12 citations
    9. Zone 1 Hepatocellular Necrosis: A Manifestation of Selenium Toxicity? The American Journal of Gastroenterology · 2009
    10. Soil, grain and water chemistry and human selenium imbalances in Enshi district, Hubei Province, China 1996 · 16 citations
    11. Absorption of Excess Selenium and Sulfur by Plants and Animals Journal American Society of Mining and Reclamation · 1995 · 7 citations
    12. Selenium and its Inorganic Compounds [BAT Value Documentation, 2011] 2019 · 1 citations
    13. Exploring the Link Between Selenium from Wheat and Hair Loss International Journal of Pharmaceutical Sciences Review and Research · 2025
    14. Scientific opinion on the tolerable upper intake level for selenium EFSA journal · 2023 · 30 citations
    15. Paradise Nut Paradox: Alopecia Due to Selenosis from a Nutritional Therapy International Journal of Trichology · 2012 · 13 citations
    16. Investigation of Some Amino Acid Analogues and Metabolites as Inhibitors of Wool and Hair Growth Australian journal of biological sciences · 1983 · 5 citations
    17. Coat Problems 2021
    18. Cyberspace Chat International Society of Hair Restoration Surgery · 2008
    19. Nutrition and hair Clinics in Dermatology · 2010 · 70 citations
    20. Peran Multivitamin terhadap Pertumbuhan dan Kesehatan Rambut: Literature Review Jurnal Ilmiah Kedokteran dan Kesehatan · 2025
    21. Selenium in the supplement as the probable cause of hair loss and nail dystrophy Journal of cosmetic dermatology (Print) · 2023 · 1 citations
    22. Selenium: When a good nutrient goes bad Integrated Environmental Assessment and Management · 2009 · 1 citations
    23. Acute bilateral vision and hearing loss following high-dose selenium ingestion: a case report Frontiers in Pharmacology · 2026
    24. Selenium Compounds and Their Bioactivities: Molecular Mechanisms and Prospects for Functional Food and Therapeutic Applications Plants · 2025 · 7 citations
    25. Dietary Aspects for Selenium and/or Selenium Compounds Molecular and integrative toxicology · 2018 · 1 citations
    26. Study on the effects of fluorine and selenium on human hair follicles in vitro Chinese Journal of Aesthetic Medicine · 2004
    27. [Apoptotic study on the effect of fluorine and selenium on the human hair follicle in vitro]. PubMed · 2007
    28. Screening and identification of efficient strain in selenium oxyanions sorption in order to biological wastewater treatment DOAJ (DOAJ: Directory of Open Access Journals) · 2016 · 1 citations
    29. Geochemistry and human selenium imbalances in China 1997
    30. Metabolism of subtoxic levels of selenium in animals and humans. PubMed · 1996 · 115 citations