21 citations
,
June 1991 in “Journal of Inherited Metabolic Disease” This case report observed that a selenium-deficient diet in a child with propionic acidaemia led to macrocytosis and hair abnormalities, which improved with selenium supplementation.
20 citations
,
February 2013 in “Nutrition” This article reviews the role of prebiotics and the potential of green tea and selenium as alternatives due to their non-toxic nature, but it reports no new research findings.
20 citations
,
August 1960 in “PubMed” This study investigated the effects of selenium sulfide suspension on hair roots after noticing higher abnormal hair root proportions in individuals using the preparation.
18 citations
,
September 2011 in “Livestock science” This study found that maternal Nano-Se supplementation in cashmere goats improved antioxidant status and promoted secondary hair follicle development in fetuses at 110 days.
16 citations
,
May 2019 in “Hormone and Metabolic Research” This systematic review found insufficient evidence to support protective effects of selenium on polycystic ovary syndrome complications, despite some studies suggesting it may reduce insulin resistance and dyslipidemia.
16 citations
,
December 2005 in “Journal of Animal Physiology and Animal Nutrition” This study found that both low and high dietary selenium levels reduced hair growth in adult dogs, with optimal growth observed at mid-range selenium concentrations.
16 citations
,
January 1996 This review discusses selenium's role in human and animal health, its deficiency's link to diseases in China, and the need for precise geochemical control data; it reports no new findings.
15 citations
,
July 1984 in “Nutrition Research” Selenium increased in hair but not in blood after taking supplements.
15 citations
,
March 1997 in “International Journal of Dermatology” In this case report, the authors describe green hair discoloration in a patient attributed to the use of selenium sulfide.
13 citations
,
October 1960 in “Experimental Biology and Medicine” This study found that small amounts of subcutaneously injected Se75 were deposited and retained in the hair of dogs for up to 316 days.
12 citations
,
June 2023 in “Journal of trace elements in medicine and biology” This study identified dose levels of selenium that can produce toxicity, noting that doses as low as 2-3 µg Se/kg bw/day can lead to adverse effects, and a human mortality study linked 300 µg/day consumption to increased death risk.
12 citations
,
July 1964 in “Archives of Dermatology” This study found that neither a single application nor prolonged exposure to selenium sulfide had a significant effect on hair growth or rest phase percentages.
11 citations
,
January 2016 in “BMC veterinary research” This study found that urinary selenium to creatinine ratio and serum selenium concentrations quickly respond to changes in dietary selenium, making them useful biomarkers for assessing selenium status in dogs.
11 citations
,
January 1993 in “Journal of Veterinary Diagnostic Investigation” This study identified chronic selenosis in horses in western Iowa due to elevated selenium intake from locally produced alfalfa hay, leading to symptoms like alopecia and hoof deformities.
10 citations
,
April 2019 in “Environmental Science and Pollution Research” In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.
9 citations
,
September 1989 in “PubMed” This study observed that selenium levels were lower in Sudanese children with malnutrition compared to healthy German children, with a good correlation between selenium and glutathione peroxidase activity.
7 citations
,
August 2025 in “Plants” This review highlights the role of plant-derived organic selenium compounds, noting their high bioavailability and low toxicity, and provides a comprehensive overview of selenium's uptake in plants and metabolism in humans, offering a theoretical basis for future nutritional research.
7 citations
,
January 1995 in “Journal American Society of Mining and Reclamation” This review discusses the forms of selenium and sulfur in soil, their plant absorption, and risks of toxicity to livestock, emphasizing selenium's role in selenosis and sulfur's link to polioencephalomalacia in ruminants; it reports no new experimental results.
7 citations
,
March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
6 citations
,
March 2011 in “Experimental Dermatology” This study found that an imbalance of selenium in a C57BL/6 mouse model led to hair loss with color change and was linked with changes in hair follicle apoptosis markers.
5 citations
,
July 2019 in “Nutrients” This study found that boys in Mexico City with selenium intake below the recommended dietary allowance had lower odds of progressing to advanced stages of pubertal development, while no association was observed in girls.
4 citations
,
January 1989 This study found that growth affects selenium deposition in hair, nails, and other tissues of adult and weanling rats, indicating dietary and physiological factors may influence selenium levels.
4 citations
,
January 2016 in “Dermatology online journal” This report describes a case of acquired yellow hair discoloration in a 77-year-old woman, potentially caused by applying selenium sulfide after bacitracin zinc to her scalp.
2 citations
,
October 1961 in “Experimental Biology and Medicine” This study found that rabbits fed a diet deficient in Vitamin E developed severe muscular dystrophy that was not fully prevented by adding selenium, Vitamin E supplements, or natural feedstuffs, indicating other nutritional deficiencies.
2 citations
,
February 1983 in “International Journal of Cosmetic Science” This study found that both hard and soft selenium disulphide-based detergents significantly increased triglyceride levels in human hair, suggesting enhanced sebum production with reduced lipolytic activity, but showed no significant differences between their effects.
1 citations
,
August 2023 in “Journal of cosmetic dermatology (Print)” This review discusses the potential link between selenium supplementation and symptoms of chronic selenium toxicity, such as hair loss and nail dystrophy, due to excess intake leading to disruptions in hair and nail protein structure.
1 citations
,
February 2021 in “Animal feed science and technology” This study found that puppies fed organic selenium had better retention of selenium compared to those fed inorganic selenium, with no significant difference in coat quality or hair growth.
1 citations
,
March 2020 in “̒Ulūm-i dārūyī” This study found that one month of selenium supplementation improved liver and kidney function biomarkers and reduced severe hair loss in patients with beta-thalassemia major.
1 citations
,
December 2019 This documentation reviews the absorption, metabolism, and excretion of selenium and its compounds, highlighting the complex interactions and health implications, but reports no new clinical results.
1 citations
,
September 2019 in “Journal of cosmetic dermatology” This study found no significant difference in serum levels of lead and selenium between patients with premature hair graying and those without it.