Soil, Grain, and Water Chemistry and Human Selenium Imbalances in Enshi District, Hubei Province, China

The document discussed selenium (Se) imbalances in Enshi District, Hubei Province, China, highlighting its dual role as both an essential trace element and a potential toxin. Selenium is crucial for human health, forming part of the enzyme glutathione peroxidase, but its narrow safe intake range necessitates careful dietary control. In China, Se deficiency was linked to Keshan Disease and Kaschin-Beck Disease, with high incidence rates in the past, though these have decreased significantly. Conversely, Se toxicity, causing hair and nail loss and nervous system disorders, was noted in specific regions, including Enshi District. The study emphasized the need for further research to identify precise geographical areas at risk and the geochemical factors influencing Se availability.