Soil, Grain, and Water Chemistry and Human Selenium Imbalances in Enshi District, Hubei Province, China

The document discussed selenium (Se) imbalances in Enshi district, Hubei Province, China, highlighting its dual role as both an essential trace element and a potential toxin. Selenium is crucial for human health, forming part of the enzyme glutathione peroxidase, which prevents cell degeneration. However, the narrow range between deficiency and toxicity levels necessitates careful dietary control. In China, Se deficiency was linked to Keshan Disease and Kaschin-Beck Disease, with high incidence rates in the past. Conversely, Se toxicity, causing hair and nail loss, was observed in Enshi District. The study emphasized the need to understand the geochemical controls on Se availability to manage exposure risks effectively.