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Apoptosis is essential for human skin development and forming a functional epidermis.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Nerves are crucial for the regeneration of various body parts in many animals.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Special fiber materials boost the healing properties of certain stem cells.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Oestrogens are key for bone growth during puberty in both boys and girls.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Estrogen therapy can reduce skin aging but has cancer risks.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.