December 2014 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This case report describes successful treatment of a four-year-old boy with kerion-type tinea capitis caused by T. mentagrophytes using griseofulvin, erythromycin, wet dressing, and ketokonazole shampoo, with improvement after 8 weeks.
March 2017 in “International journal of current advanced research” This study evaluates the effectiveness of medicated shampoo against hair loss using a questionnaire distributed to 100 people, but it reports no new clinical results.
10 citations
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May 2017 in “CMAJ. Canadian Medical Association journal” The boy had a fungal scalp infection called kerion, which was cured with oral antifungal medication.
10 citations
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June 2001 in “International Journal of Cosmetic Science” This study found that laboratory-formulated natural shampoos condition hair better than commercial herbal shampoos, as shown by SEM micrograph analysis of hair microstructure.
May 2026 in “Riset Informasi Kesehatan” This experimental study evaluated shampoo formulations with varying concentrations of candlenut oil, concluding that the 12% formulation (Formula 2) demonstrated optimal physical characteristics and quality standards, with acceptable pH and viscosity but reduced foam stability at higher oil concentrations.
This study found that while many shampoo ingredients are marketed as effective against hair loss, only caffeine, adenosine, placental proteins, and melatonin have moderate clinical evidence for efficacy, and a majority of other claimed active ingredients lack clinical trial verification.
August 2021 in “Journal of the American Academy of Dermatology” This study reported that an anti-hair loss shampoo containing six active ingredients activated the Wnt/β-catenin pathway in human hair follicle dermal papilla cells in vitro.
This study explored the formulation of a 1% minoxidil gel shampoo, finding that specific combinations of surfactants significantly affect its foaming ability, which may enhance compliance compared to imported products.
December 2022 in “Scientific Reports” This study found that caffeic acid amide derivative, compound 4, effectively inhibited steroid 5α-reductase type 1 in vitro, suggesting potential for development as a treatment for androgenic alopecia.
September 2010 in “Reactions weekly” The combination of tretinoin, minoxidil, and betamethasone valerate may cause severe scalp inflammation.
January 2025 in “Journal of Fungi” This case report highlights the importance of early mycological diagnostics, supported by dermoscopy and ultraviolet-enhanced fluorescence dermoscopy, in preventing scarring from kerion celsi-associated hair loss in children.
9 citations
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June 2011 in “International Journal of Cosmetic Science” This study found that a commercially available shampoo significantly increased hair counts and reduced hair shedding in Korean subjects with alopecia over 16 weeks.
January 2025 in “International Journal of Pharmacognosy and Clinical Research” This study reported the development of a scalp serum containing Beta-Sitosterol and nutrient-rich oils, showing stable physicochemical properties, suggesting potential for promoting hair growth and scalp health, though further clinical testing in humans is needed to confirm effectiveness.
June 1996 in “Journal of Dermatological Science”
June 2022 in “International Journal of Advanced Research in Science, Communication and Technology” In this study, a herbal shampoo containing fermented rice water and various traditional herbs was found to exhibit good foaming ability, cleansing properties, and was effective in treating hair loss.
January 2022 in “Clinical Cases in Dermatology” This case report describes successful treatment of a 7-year-old girl with gray patch tinea capitis using oral micronized griseofulvin and topical ketoconazole shampoo, resulting in complete clinical and microscopic clearance.
11 citations
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May 2010 in “Annals of the Academy of Medicine Singapore” This case report describes a 4-year-old girl in Singapore with inflammatory tinea capitis, which improved with oral griseofulvin and selenium sulfide shampoo.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a bael-based herbal shampoo formulation demonstrated effective cleansing, foaming ability, and stability, with antimicrobial properties that may benefit scalp health, positioning it as a promising natural alternative to synthetic shampoos.
1 citations
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June 2018 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case study reports that combining skin debridement with topical and systemic antifungals improved treatment outcomes for kerion celsi in a 5-year-old boy, preventing scarring alopecia.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and tested an herbal antidandruff shampoo using plant extracts like neem, fenugreek seed, aloe vera, and clove, demonstrating antibacterial and antifungal activity against common scalp microbes and offering a potential natural alternative for dandruff treatment.
August 2020 in “Prosiding Farmasi” This study reviewed existing literature and reported that 1% Zinc pyrithione in anti-dandruff shampoo effectively inhibits the growth of fungi responsible for dandruff, aligning with the regulatory limits set by Indonesian health authorities.
4 citations
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March 2022 in “Journal of Cosmetic Dermatology” This study found that formulations containing saccharide isomerate significantly improved scalp flaking, sebum secretion, and transepidermal water loss compared to placebo in an adult Chinese population with dandruff.
In a harbor seal from the Yellow Sea of Korea, this study found that alopecia-related lesions disappeared completely after treatment with internal and external ketoconazole, povidone iodine, cephalexin, and multivitamins over 8 months.
1 citations
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August 2017 in “Journal of food and nutrition research” This study found that the black bean-licorice-biotae folium extract may improve hair diameter, scalp moisture, and sebum secretion, although its effect on hair density was not significant.
This study found that dermoscopy combined with calcium fluorescent white staining effectively aided in the early diagnosis and treatment evaluation of tinea capitis by highlighting specific hair changes and fluorescent patterns associated with different dermatophyte infections in a sample of 20 patients.
6 citations
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January 2023 in “Medical Mycology Journal” In this case study of a 64-year-old woman with kerion celsi caused by Microsporum canis, treatment with the oral antifungal fosravuconazole resulted in symptom resolution without scarring or side effects over 12 weeks, suggesting its potential effectiveness for various dermatomycoses.
28 citations
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December 2003 in “Medical Hypotheses” This paper suggests that ketoconazole 2% shampoo may enhance finasteride's effectiveness in treating androgenetic alopecia by more completely inhibiting the dihydrotestosterone pathway.
1 citations
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October 2020 in “Cermin Dunia Kedokteran” This study reported complete clinical clearance of tinea capitis in a 3-year-old boy after 8 weeks of treatment with oral griseofulvin and ketoconazole shampoo.
January 2025 in “Molecules” In this review, the authors discuss caffeine's potential mechanisms and benefits as a hair loss treatment, noting its possible effectiveness and safety, though they caution that existing studies often have significant design flaws.
July 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that the liposomal Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss compared to placebo over 180 days, enhancing factors such as hair density, thickness, growth rate, and tensile strength, with no related adverse events reported.