Evaluation of the Active Ingredient Complex of an Anti-Hair Loss Shampoo on the Activation of Wnt/β-Catenin Pathway in Human Hair Follicle Dermal Papilla Cells

The study aimed to evaluate the effect of a combination of six active ingredients in an anti-hair loss shampoo on the activation of the Wnt/β-catenin pathway in human hair follicle dermal papilla cells (HHFDPCs). The Wnt/β-catenin pathway is essential for hair growth as it influences stem cell renewal and the production of factors necessary for hair follicle development. The active ingredients tested were biotin, hydrolyzed wheat protein, dexpanthenol, pyridoxine, tocopheryl nicotinate, and ruscus extract. The study was conducted in vitro, meaning it was performed with cells outside their normal biological context. The document does not provide the results or the number of samples tested, so the effectiveness of the shampoo ingredients on the Wnt/β-catenin pathway activation cannot be determined from the summary provided.