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High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.

The cause and importance of misplaced oil glands in the hair follicle are not well understood.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Cathepsin L is essential for normal hair growth and development.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Hormonal therapies are safe and effective for treating adult women's acne.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.