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    Glossary Sebaceous Tumors

    abnormal growths originating from sebaceous glands

    Sebaceous tumors, also known as sebaceous neoplasms, are abnormal growths that originate from the sebaceous glands, which are responsible for producing the oily substance called sebum that lubricates the skin and hair. These tumors can be benign, such as sebaceous adenomas, or malignant, like sebaceous carcinoma, and they may appear as small, yellowish bumps on the skin. Early detection and diagnosis are crucial, especially for malignant forms, as they can be aggressive and may require surgical removal or other treatments.

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    1. Lrig1 Expression in Human Sebaceous Gland Tumors Dermatopathology · 2016 · 3 citations
    2. Development and homeostasis of the sebaceous gland Seminars in Cell & Developmental Biology · 2012 · 107 citations
    3. Histopathological Findings and Proliferative Activity of Canine Sebaceous Gland Tumours with a Predominant Reserve Cell Population Journal of Comparative Pathology · 2015 · 5 citations
    4. 724 MPZL3 functions as a negative regulator of sebaceous gland size and sebocyte proliferation 2022
    5. Trichoblastoma with sebaceous and sweat gland differentiation 2001 · 12 citations
    6. Stem and progenitor cells in sebaceous gland development, homeostasis and pathologies Experimental dermatology · 2021 · 19 citations
    7. 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation Journal of Investigative Dermatology · 2023
    8. An immunohistochemical study of the apocrine type of cutaneous mixed tumors with special reference to their follicular and sebaceous differentiation Journal of Cutaneous Pathology · 1999 · 54 citations
    9. Expression of androgen receptors in skin appendage tumors: An immunohistochemical study Journal of Cutaneous Pathology · 1995 · 40 citations
    10. Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression Cell Reports · 2013 · 15 citations
    11. Histopathological analysis of skin adnexal tumors at tertiary care hospital International Journal of Clinical and Diagnostic Pathology · 2025
    12. Benign skin tumors 2016
    13. Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity Cell reports · 2016 · 54 citations
    14. Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity 2023
    15. Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity Cancer Research · 2006 · 70 citations
    16. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    17. Lectin‐binding profiles for normal skin appendages and their tumors Journal of Cutaneous Pathology · 1992 · 18 citations
    18. Inflammatory and non-melanocytic tumoral pathology of the nail Pathology · 2014
    19. Tumor necrosis factor-alpha inhibitor associated psoriasiform alopecia (drug-induced psoriasiform alopecia) Informa Healthcare eBooks · 2012 · 1 citations
    20. Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity 2023
    21. Sex Steroid Hormone Receptors in Human Skin Appendage and its Neoplasms Endocrine Journal · 2005 · 59 citations
    22. Comprehensive Genomic Profiling of Cutaneous Adnexal Carcinomas: A Genomic Landscape Study Dermatopathology · 2026
    23. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015 · 46 citations
    24. Dermal Adnexal Neoplasms: Exploring Rare Variants and Their Clinical Behavior International Journal of Drug Delivery Technology · 2026
    25. Cutaneous Tumours of Pilar Origin with Associated Syndromes Research Review · 2023
    26. Phospholipase C 1 is required for skin stem cell lineage commitment The EMBO Journal · 2003 · 101 citations
    27. The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development The EMBO Journal · 2007 · 125 citations
    28. Epidermal Notch signalling: differentiation, cancer and adhesion Current opinion in cell biology · 2008 · 253 citations
    29. Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis Dermatology and Therapy · 2021 · 78 citations
    30. Ultraviolet B irradiation increases the expression of inflammatory cytokines in cultured sebocytes Journal of Dermatology · 2013 · 20 citations