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Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Targeting hair follicles can improve skin treatments and reduce side effects.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.

Finasteride improves hair loss in women with hyperandrogenism.

Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.

Wool follicles are complex, involving interactions between different cell types and structures.

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Stem cells from hair follicles can safely treat hair loss.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.