August 2021 in “Journal of Fundamental and Applied Pharmaceutical Science” In this study, a 5% black tea extract hair tonic showed hair growth-promoting activity in rabbits, achieving 9.62 mm growth by day 18, with all tested formulas proving physically stable.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a herbal mehendi gel using natural plant-based ingredients aimed at providing sustainable hair coloring and scalp care. The formulation demonstrated beneficial properties including natural hair coloring, scalp conditioning, antimicrobial activity, antioxidant action, and safety with no observed skin irritancy.
January 2023 in “Health science reports” In this study, oral Pycnogenol® intake was reported to significantly increase hair density and improve scalp microcirculation in Han Chinese menopausal women over six months.
This study found that an exosome formulation with plant extracts significantly increased hair regrowth in men with male pattern alopecia compared to a placebo, without notable adverse effects.
January 2022 in “Pharmaceutical Sciences Asia” This study found that alcoholic extracts from Clitoria ternatea flowers increased the proliferation of human dermal papilla cells and stimulated initial hair growth in mice, with effects similar to minoxidil.
September 2025 in “Journal of King Saud University - Science” This study found that Lophocereus marginatus extracts significantly inhibited melanoma cell growth in vitro and stimulated hair growth in mice, with combined treatments of LM with minoxidil or bergamot showing notable effects by day 14 without altering body weight.
1 citations
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December 2021 in “The Open Dermatology Journal” This study found that a herbal hair oil formulation from various plants showed good hair growth and weight without irritation, suggesting potential for improving hair growth.
July 2014 in “Americanae (AECID Library)” This study found that extracts from Tridax procumbens and Ouratea spectabilis reduced seed germination and inhibited root and hypocotyl growth in lettuce, indicating potential allelopathic effects.
August 2019 in “Pharmacoscript” This study found that a 3:2 combination of pandanus and sansevieria leaf extracts showed the best hair growth activity compared to using each extract alone.
August 2026 in “Biology Bulletin Reviews” This study found that extracts from Avicennia marina, Moringa oleifera, and Calotropis procera demonstrated strong antibacterial, antioxidant, and hair-growth-promoting properties, with A. marina showing the most pronounced effects.
April 2014 in “동의생리병리학회지” This study found that Samhwang-Sasimtang herbal extract may enhance hair growth in mice, as indicated by increased hair follicle activity and reduced growth inhibition factors compared to a control.
4 citations
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August 2018 in “International Journal of Current Microbiology and Applied Sciences” This study identified various phytochemicals and compounds in Eclipta prostrata leaves using qualitative tests, FTIR, and GC-MS analysis, highlighting the presence of phytol and squalene among others.
1 citations
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December 2014 in “International Journal of Pharmacy and Pharmaceutical Sciences” The study observed that Carthamus tinctorius extract-loaded lipid carriers promoted hair growth in C57BL/6 mice more effectively than minoxidil, although further research on humans is needed for confirmation.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study formulated and evaluated a herbal hair growth serum with rosemary oil as the main active ingredient, alongside vitamin E, rose water, polysorbate 20, and propylene glycol. The serum exhibited satisfactory physicochemical properties, including a pH of 5.73, specific gravity of 0.9947, good spreadability, and a low microbial count of 0.5 CFU/mL. It showed a slightly translucent appearance with a characteristic odor. While the serum demonstrated promising characteristics for scalp and hair care, further studies are needed to assess its long-term stability and effectiveness in promoting hair growth.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study formulated and evaluated a herbal hair growth serum with rosemary oil as the main active ingredient, alongside vitamin E, rose water, polysorbate 20, and propylene glycol. The serum exhibited satisfactory physicochemical properties, including a pH of 5.73, specific gravity of 0.9947, good spreadability, and a low microbial count of 0.5 CFU/mL. It showed a slightly translucent appearance with a characteristic odor. While the serum demonstrated promising characteristics for scalp and hair care, further studies are needed to assess its long-term stability and effectiveness in promoting hair growth.
September 2025 in “Journal of Applied Biological Chemistry” In a laboratory study, Grateloupia elata extract demonstrated antioxidant and anti-aging effects by scavenging free radicals, inhibiting collagenase and elastase, increasing procollagen production, and reducing MMP-1 secretion, suggesting its potential use in functional cosmetics.
This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
20 citations
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August 2015 in “International Journal of Molecular Medicine” This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.
April 2022 in “Jurnal Penelitian Farmasi dan Herbal” In this study, hair tonic containing 15% patchouli leaf extract showed the greatest hair growth in rabbits, with higher concentrations leading to faster regrowth.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review details how herbal hair serums, which use plant-derived oils and extracts like Aloe vera and coconut oil, can improve hair growth, reduce hair loss, and protect hair from damage, responding to rising consumer interest in natural and sustainable cosmetic products.
November 2025 in “Essential Chem” In this study, Eclipta alba extract showed potential for hair regrowth by increasing the proliferative activity of human dermal papilla cells by 45% in vitro, with evidence suggesting activation of the Wnt signaling pathway.
5 citations
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February 2010 in “Drug development and industrial pharmacy” This study found that vesicles formed with behenyltrimethylammonium chloride, stearic acid, and hinokitiol significantly improved skin permeation of hinokitiol in vitro, which may aid in hair growth promotion.
In a study on female Wistar rats, researchers found that a hair tonic containing a 7.5%:2% combination of talok and pare leaf extracts increased hair growth comparable to minoxidil, showing similar efficacy in promoting hair growth without significant statistical difference.
19 citations
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January 2023 in “ACS Omega” This study developed sodium alginate and epigallocatechin gallate cryogels cross-linked with ferric ions, showing that they have strong antibacterial properties and rapid hemostatic abilities, making them promising candidates for wound dressing applications.
November 2024 in “Applied Sciences” This study suggests that a supercritical CO2 extract from wild-strawberry-processing waste may be an innovative and sustainable ingredient for cosmetic applications, particularly in treating androgenic-related skin conditions.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers observed that extracts from rosemary (including essential oil, hydrolate, and alcoholic extract) significantly promoted hair growth in male mice, surpassing the effects of the commercial drug minoxidil.
67 citations
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January 2007 in “Environmental health perspectives” This case report highlights that a woman experienced arsenic toxicosis from kelp supplements, manifesting as alopecia and memory loss, which resolved after stopping the supplements.
April 2026 in “International Journal of Drug Delivery Technology” In this study, phytochemical analysis and molecular docking suggested that bioactive compounds in several Ayurvedic herbs may interact persistently with hair growth and antifungal protein targets, indicating potential as plant-based treatments for dandruff and hair loss.
3 citations
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August 2021 in “The Open Dermatology Journal” This study found that the formulated herbal hair serum improved hair growth and hair weight with minor sensitivity after application and demonstrated stability for seven days.
September 2026 in “International Journal for Research in Applied Science and Engineering Technology” This review discusses the potential benefits of rosemary-based hair growth serums, noting that rosemary oil showed comparable results to 2% minoxidil in improving hair parameters for androgenetic alopecia, though more research is needed on standardized formulations.