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c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.

People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.

White hair follicles in vitiligo have fewer and less functional melanocytes.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Lower growth factors linked to balding in androgenetic alopecia.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Sonicated platelet-rich plasma boosts hair growth by activating stem cells.

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Scientists found cells in hair that are key for growth and color.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Gambogic Amide helps maintain hair color and promotes hair growth.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Gray hair can potentially be reversed, leading to new treatments.

Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.

Dermal factors are crucial in regulating melanin production in skin.

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

DHT stops hair regrowth in mice, similar to human hair loss.

Certain mice without specific receptors or mast cells don't lose hair from stress.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.