179 citations,
June 2000 in “The American journal of pathology” The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.
57 citations,
August 1999 in “Archives of dermatology” Hair follicles grow hair and release it through the skin.
54 citations,
January 2009 in “British Journal of Dermatology” Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
44 citations,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
37 citations,
June 2011 in “Journal of The American Academy of Dermatology” Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.
29 citations,
July 2008 in “Journal of Cutaneous Pathology” Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
28 citations,
January 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Women with scarring alopecia have a lower quality of life and more anxiety and depression than those with non-scarring alopecia.
27 citations,
January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
24 citations,
September 2018 in “Lasers in Surgery and Medicine” Multiphoton microscopy can non-invasively tell apart scarring from non-scarring hair loss and could aid in treatment.
20 citations,
May 2016 in “Journal of Cutaneous Pathology” Using CD123 to detect certain immune cells helps diagnose a type of hair loss condition.
19 citations,
May 2021 in “Clinical, Cosmetic and Investigational Dermatology” Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
19 citations,
February 2013 in “The American Journal of Dermatopathology” Nonscarring alopecia has higher hair density than scarring alopecia, and hair density can help diagnose the type of alopecia.
18 citations,
July 2001 in “International Journal of Dermatology” A 12-year-old boy's hair loss and skin issues improved significantly with medication.
17 citations,
January 2020 in “Skin appendage disorders” Certain diets may help with hair growth in people with different types of hair loss.
17 citations,
May 2016 in “Archives of Dermatological Research” Reflectance confocal microscopy can help tell apart scarring from non-scarring hair loss.
14 citations,
December 2013 in “Anais Brasileiros De Dermatologia” A woman with long-term scalp psoriasis developed rare scarring hair loss that didn't fully respond to treatments.
13 citations,
March 2011 in “British Journal of Dermatology” A woman with scalp lymphoma and hair loss improved with radiotherapy, highlighting the need for biopsies in similar cases.
13 citations,
April 2001 in “International Journal of Dermatology” Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.
11 citations,
January 2012 in “Archives of Dermatology” Polarized microscopy is a quick and free method to correctly identify types of hair loss.
11 citations,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Hair transplant and applying 5% minoxidil solution can effectively treat permanent hair loss, but it may change hair direction in some cases.
10 citations,
June 2015 in “Seminars in cutaneous medicine and surgery” Hair loss can be caused by various factors, and treatments focus on restoring normal hair growth.
8 citations,
January 2008 in “PubMed” Mesotherapy for the scalp can cause severe infections, fat tissue death, and permanent hair loss.
6 citations,
March 2018 in “Proceedings - Baylor University. Medical Center” Sarcoidosis can cause severe high calcium levels, hair loss, and kidney failure.
6 citations,
May 2013 in “Journal of Clinical Oncology” Combining Ficlatuzumab and Gefitinib can cause severe hair loss.
5 citations,
February 2017 in “Australasian Journal of Dermatology” Scarring hair loss found in female pattern; biopsy needed for diagnosis.
4 citations,
January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
4 citations,
November 2016 in “Journal of Cutaneous Pathology” Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.
4 citations,
July 2015 in “Case Reports in Dermatology” A woman with unexplained hair loss was found to have harmless skin tumors and a scarring hair loss condition, but the tumors didn't cause the hair loss.
4 citations,
November 2021 in “Biomedicines” New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.
3 citations,
October 2021 in “Indian Journal of Plastic Surgery” Early diagnosis and aggressive treatment are important for managing scarring alopecia; hair transplantation's effectiveness is uncertain.