Lichen Planopilaris (Scarring Alopecia) in a Child

    Virendra Sehgal, Pramila Bajaj, G Srivastva
    TLDR A 12-year-old boy's hair loss and skin issues improved significantly with medication.
    The document described a case of lichen planopilaris, a type of scarring alopecia, in a 12-year-old boy who experienced progressive patchy hair loss on the scalp, accompanied by dusky blue eruptions on the upper lip and eyebrows. Examination revealed plaques of alopecia with smooth, shiny, atrophic skin and erythema, along with erythematous, scaly, follicular papules. Histological analysis showed hyperkeratosis, hypergranulosis, and a band-like lymphohistiocytic infiltrate. Treatment with ultramicronized griseofulvin and prednisolone for 6 months, supplemented with topical betamethasone dipropionate, resulted in an excellent response, with a noticeable decline in the inflammatory infiltrate.
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      in Research/Science  98 upvotes 1 month ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.
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      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      in Research/Science  57 upvotes 2 weeks ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

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      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 7 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

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