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The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.

Certain medications, especially 5-α reductase inhibitors and neuropsychiatric drugs, are often linked to erectile dysfunction.

Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

All four treatments for early rheumatoid arthritis had similar safety profiles.

Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Current treatments for alopecia show no significant long-term benefits.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.

Cyclosporin A helps damaged hair follicles regrow hair quickly.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.