research Acute Sensitivity of the Oral Mucosa to Oncogenic K-ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
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research A Unique Presentation of Ovarian Steroid Cell Tumor Causing Hyperandrogenism in a Postmenopausal Woman
Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research Efficacy and Safety of Methotrexate in Alopecia Areata
Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
research Fatal Autoimmunity Results from the Conditional Deletion of Snai2 and Snai3
Deleting Snai2 and Snai3 causes fatal autoimmunity.
research Stem Cell Translation And Bioethics
The document concludes that stem cell therapies lack solid proof of effectiveness, except for blood system treatments, and criticizes the ethical issues and commercial exploitation in the field.
research Kinetics of Titan Cells Generation and Transcriptome Modifications Comparing Three In Vitro Protocols
Three different methods were compared for creating Titan cells, a type of fungus cell. The OZ method made the most cells initially, but the number dropped quickly. The EB method also made a lot of cells, but the number also dropped. The AA method made fewer cells, but the number stayed steady. The methods also affected which genes were active in the cells.
research Treatments for Alopecia Areata: A Network Meta-Analysis
The analysis aims to identify the most effective and safest treatments for alopecia areata.
research Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis
Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma
Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.
research Time to Loss of Response for Dupilumab in Ophiasis-Pattern Alopecia Areata
Dupilumab helped a woman with severe hair loss regrow her hair quickly and maintain it for six months after stopping treatment.
research A Hair Loss Pandemic: 19 Cases of COVID-19 Induced Telogen Effluvium
COVID-19 can cause hair loss in both severe and mild cases, often affecting women.
research Author Response: Interplay of Opposing Fate Choices Stalls Oncogenic Growth in Murine Skin Epithelium
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
research Development and Evaluation of Finasteride-Loaded Ethosomes for Targeting the Pilosebaceous Unit
Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.
research Hair, Hormones, and High-Risk Prostate Cancer
Men with a certain baldness pattern at age 40-50 may have a higher risk of aggressive prostate cancer.
research Divergent Neuroactive Steroid Responses to Stress and Ethanol in Rat and Mouse Strains: Relevance for Human Studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
research Stability Studies of Antiandrogenic Compounds in Curcuma Aeruginosa Roxb. Extract
Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.
research Profile of Tofacitinib Citrate and Its Potential in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance
T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
research The Structure and Organization of Lanceolate Mechanosensory Complexes at Mouse Hair Follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research Hair Regrowth Treatment Efficacy and Resistance in Androgenetic Alopecia: A Systematic Review and Continuous Bayesian Network Meta-Analysis
ALRV5XR is the most effective hair regrowth treatment at 24 weeks.
research Toxicity of the Pharmaceuticals Finasteride and Melengestrol Acetate to Benthic Invertebrates
Finasteride harms invertebrates' survival and burial ability.
research 12-Methoxy Carnosic Acid Efficacy Determination and Optimization Through Computational Tools for 5-Alpha Reductase Enzyme and Using Finasteride as Reference Molecule
12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.
research The Nominal Trial: Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of Topical 5% Minoxidil Lotion Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects With Hair Loss
The 5% minoxidil lotion without propylene glycol is effective, well-tolerated, and cosmetically acceptable for hair loss.
research Transformation of Amnion Epithelium into Skin and Hair Follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
research Nonpigmented Hair Removal Using Photodynamic Therapy in Animal Model
Photodynamic therapy can remove nonpigmented hair in mice and might work for humans.