October 2012 in “Ain-Shams Journal of Surgery” This study found that inserting follicular units in a specific direction during hair restoration surgery did not improve natural-looking outcomes, as hair could be styled freely with regular combing.
June 2026 in “JEADV Clinical Practice” This review synthesizes cases of biopsy-confirmed alopecia areata occurring in patients using IL-17 or IL-23 inhibitors, suggesting the need for increased awareness and further investigation into this rare adverse event.
45 citations
,
January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.
April 2019 in “Journal of Investigative Dermatology” This study found that activating the Sonic hedgehog pathway in scarring wounds can redirect wound repair to favor hair follicle regeneration instead of fibrosis.
1 citations
,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that manipulating Wnt/β-catenin signaling in embryonic mammary glands impacted their development, with high activity levels hindering branching and potentially redirecting cells toward hair follicle identity instead of mammary tissue.
This study suggests that exogenous retinoic acid can alter the morphogenesis pathway of developing skin appendages when applied during the placodal stage, leading to changes like feather formation in atypical regions of chick embryos.
200 citations
,
November 1997 in “Planta” This study found that while a tip-focused calcium gradient influences localized growth in root hairs and pollen tubes, it is not the primary determinant of growth direction in root hairs of Arabidopsis thaliana.
3 citations
,
September 2014 in “SpringerPlus” This study suggests that hair loss was a metabolic adaptation allowing hominids to evolve larger brains by alleviating dietary restrictions on essential amino acids for hair and brain development.
November 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers engineered ventral skin organoids (vSkOs) with specific cellular compositions and signaling environments to generate human amnion-like tissues called Amnioids, offering new tools for studying human development and potential regenerative therapies.
73 citations
,
April 2017 in “Scientific Reports” In this study, nitrogen starvation in Chlorella sp. FC2 IITG led to increased lipid accumulation by altering the expression of enzymes involved in various metabolic pathways, suggesting potential for genetic engineering of microalgae.
41 citations
,
November 1993 in “Journal of The American Academy of Dermatology” This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” This article discusses the advances in understanding wound-induced hair follicle neogenesis (WIHN) and highlights the roles of specific signaling pathways and cellular plasticity, noting no clinical results but suggesting potential areas for further research.
19 citations
,
November 2018 in “Nutrients” This study reports that polyphenols from Annurca apples may safely promote hair growth and protect against chemotherapy-induced alopecia without interfering with chemotherapy regimens.
14 citations
,
October 2015 in “Neurochemistry International” This study found that letrozole, an aromatase inhibitor, reduced the incidence and severity of PTZ-induced kindling seizures in mice, potentially due to its effects on 17β-estradiol and neurosteroid synthesis.
1 citations
,
April 2023 in “Science Advances” This study found that sustained ERK activity during tissue regeneration in spiny mice is linked to fibroblast growth factor and ErbB signaling, while inhibiting ERK shifted regeneration toward scarring.
1 citations
,
February 2004 in “Dermatologic Surgery” This study found that using deep plane fixation during scalp surgeries significantly reduced closure tension and allowed for increased tissue excision compared to standard techniques without fixation.
June 2023 in “British Journal of Dermatology” In this study, researchers evaluated online resources for psychological support for alopecia areata patients and found the quality lacking, with most resources not providing adequate advice or referring to therapies like cognitive behavioral therapy, despite the significant psychological impact of the condition.
February 2004 in “Dermatologic Surgery” This study found that deep plane fixation in scalp surgeries allowed for tension-reduced wound closures and increased tissue excision compared to techniques without deep plane fixation.
9 citations
,
March 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study developed a novel multi-scale image descriptor using dictionaries for classifying histological images, achieving average recall and precision measures of 0.81 and 0.86 in identifying specific skin structures and pathologies.
3 citations
,
October 2018 in “Revista de Chimie” This review discusses the potential medicinal properties and pharmacokinetic features of nettle compounds ursolic acid and quercetin, highlighting quercetin as a promising candidate for antioxidant and anti-aging effects, but reports no new clinical results.
2 citations
,
October 2015 in “Mikrobiyoloji bülteni” This case report describes a 20-year-old female with favus caused by T. schöenleinii, which initially improved with antifungal treatment but recurred due to poor adherence, underscoring favus as an ongoing health issue in Turkey.
February 2012 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study observed nestin-GFP expressing stem cells in the hair follicle bulge of living mice using high-resolution in-vivo multiphoton tomography, allowing migration tracking within their natural skin environment.
July 1999 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” In this study, researchers observed bright colored patches in the hair of diabetic patients under cross polarized light, suggesting a potential non-invasive diagnostic method for diabetes.
317 citations
,
April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This review discusses polycystic ovary syndrome, its detection, and treatments, concluding that lifestyle changes may offer sustainable management, although it reports no new clinical results.
232 citations
,
December 2011 in “Journal of the American Academy of Dermatology” Understanding and targeting specific molecules can help reduce scarring and promote scar-free healing.
157 citations
,
September 2012 in “Journal of the American Academy of Dermatology” In this retrospective cohort study, researchers reported that 11.5% of patients with DRESS developed significant long-term autoimmune or renal sequelae, with age influencing the type of sequelae observed.
150 citations
,
April 1997 in “Journal of Investigative Dermatology” 144 citations
,
May 1990 in “Journal of the American Academy of Dermatology” 140 citations
,
August 2010 in “Pigment Cell & Melanoma Research” This article discusses mouse genetic studies to explore factors influencing melanogenesis, highlighting pH and cysteine's roles, and proposes a hypothesis for human hair color diversity; it reports no new results.
125 citations
,
February 2007 in “Journal of the American Academy of Dermatology” This study found that adding topical eflornithine to laser hair removal significantly improved the reduction of unwanted facial hair in women over a 6-month period, compared to laser treatment alone.