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Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.

Alopecia areata may be linked to hearing problems, so patients should monitor their hearing.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Erbium YAG laser treatment, combined with conventional therapy, can effectively reduce hair loss and promote hair growth in men with androgenetic alopecia.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Mutant mice help researchers understand hair growth and related genetic factors.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Vitamin D3 affects cell differentiation in specific skin areas.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.