Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review summarizes the therapeutic potential and development of engineered extracellular vesicles for tissue repair and regenerative medicine, reporting no new clinical findings.

This review discusses androgen receptor targeting as a potential treatment strategy for triple-negative breast cancer and reports no new experimental outcomes.

This study found that activating liver X receptors with an agonist reduced skin fibrosis in experimental models, particularly in inflammation-driven conditions, by inhibiting macrophage infiltration and interleukin-6 release.

Hair follicle stem cells may help repair the brain after a stroke.

This study suggests that mouse lineage specification during pre-implantation development involves distinct timing and mechanisms for trophectoderm and inner cell mass differentiation, challenging existing models.

This study identified and characterized human hair-specific keratin genes, revealing their sequence homology with mouse counterparts and expression in hair follicle precortical cells.

This review explores biomaterials in non-viral gene delivery systems and highlights the need for more research to better understand how various parameters affect gene delivery processes, without reporting new experimental results.

This study demonstrates that modeling clone size independently of time offers analytical advantages for understanding cell distribution and mutation frequency in epithelial progenitors, extending applications beyond neutral models.

This review summarized advancements in intestinal lymphatic drug delivery, emphasizing the evolving understanding of lymphatics as active players in health and disease, which has led to innovative therapeutic strategies and enhanced pharmacokinetic outcomes via this delivery route.

Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.

This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.

This study found that purified humic acids from oxidized coal enhance plant growth by modulating oxidative stress and influencing photobiological processes, with improved root growth and enzyme activity linked to antioxidant and pro-oxidant properties.

This study found that mice lacking the CXCR2 receptor regenerated tissue scarlessly in various injury models and that administering plasma or G-CSF from these mice to wild-type mice also reduced scarring, suggesting potential therapeutic strategies to improve human skin wound healing.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

This review highlights recent advances in ultrasound-based radiomics and radiogenomics for ovarian cancer, suggesting these techniques improve diagnostic accuracy and patient-specific treatment strategies, despite ongoing challenges with standardization and model interpretability.

This study found that maize root hairs respond differently to cold stress based on severity, with mild cold allowing limited growth through adaptive remodeling, while severe cold causes more pronounced inhibition and prioritizes stress defense, affecting transcriptome and morphology.

This study observed that numerical chromosomal aberrations were more common in men with severe male factor infertility and azoospermia compared to those with other sperm quality issues, while chromosomal translocations were significantly associated with oligoasthenozoospermia, highlighting important genetic counseling considerations.

In this study, researchers observed that metabolite expression patterns, including sugars, lipids, amino acids, and nucleotides, affect hair follicle growth in cashmere goats, with feeding practices potentially influencing these cycles via hormone and vitamin levels.

This review discusses the mechanisms behind alopecia during anticoagulation therapy and current treatments but reports no new clinical results.

Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.

This case report describes a 4-year-old boy with Netherton syndrome, where trichoscopy importantly aided diagnosis and is recommended for all children with erythroderma.

This study found that dracorhodin perchlorate improved wound healing in diabetic rats by regulating the TLR4 pathway and related inflammatory factors.

This study found that the oral JAK inhibitors ritlecitinib and brepocitinib were effective in maintaining hair regrowth in alopecia areata with continuous use, though efficacy decreased after withdrawal.

This article discusses the rationale, design, major findings, and updated objectives and methods of the ongoing Rotterdam Study on various diseases, without reporting new research results.

This review discusses the preliminary results of using rotational thrombectomy for acute dialysis-access graft occlusion in the upper extremity, reporting no new clinical outcomes.

This study concluded that the receptor-like kinase ERULUS, regulated by auxin, is crucial for modulating cell wall composition and pectin dynamics during root hair growth in Arabidopsis.

This case report describes common thyroid disorders in a β-thalassemia patient with frequent blood transfusions, emphasizing the need for monitoring thyroid function in such patients.

In this study, researchers characterized the retinal structure and function of the Oat^rhg mouse model of gyrate atrophy, finding localized atrophy without significant retina-wide functional impact, suggesting the model may be useful for testing new treatments using multimodal retinal imaging.