2 citations
,
February 2022 in “Research Square (Research Square)” This study found that the ethanolic root extract of Onosma dichroantha exhibits antioxidant activity and significant antimicrobial effects against 11 bacterial species.
1 citations
,
June 2017 in “International Journal of Toxicology” This symposium reviewed strategies to advance stalled drug molecules, discussed common regulatory hurdles, and explored options for repurposing drugs, but it reported no new research findings.
November 2025 in “Frontiers in Animal Science” This study established a predictive model for water intake in hair sheep, finding significant associations with dry matter and its intake but not with sex classes, suggesting a more accurate and efficient way to predict and manage water use in these animals.
February 2025 in “Global Academic Journal of Pharmacy and Drug Research” This study reported that compounds from the root of Beta vulgaris, specifically 4-picoline and Betalain, showed potential as effective anti-hair loss treatments by demonstrating significant inhibitory activity against the enzyme 5α-reductase in a computational molecular docking study.
This article explores how natural and man-made factors shape architecture and environments in emergency situations, focusing on principles relevant to Kazakhstan's specific conditions. Results are not reported.
July 2022 in “Research Square (Research Square)” This study found that miR-23b and miR-133 significantly reduce mRNA and protein levels of specific target genes involved in Merino sheep hair follicle development, providing insight into molecular breeding for fine wool production.
September 2021 in “Research Square (Research Square)” This study reports that despite rescuing neurulation and skin barrier defects, Grhl3 gene overexpression in mice leads to hearing impairment, hair loss, and other developmental abnormalities, highlighting low tolerance for Grhl3 dysregulation.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that orally administering the CCR5 inhibitor Maraviroc improved hair loss in 4 out of 5 mice with alopecia areata and also reduced the development of the condition, evidenced by decreased CCR5+ T-cell infiltration in treated mice.
14 citations
,
March 2019 in “Plant methods” This study introduced a new adaptive microrhizotron for non-destructive observation of pepper root traits, finding that specific installation patterns significantly enhanced root interception probability while effectively measuring root architecture for plant research.
4 citations
,
February 2012 in “Chinese Science Bulletin” In this study, overexpression of the MtAnn3 gene in Medicago truncatula roots was associated with altered root hair growth polarity in a calcium-free environment.
1 citations
,
April 2025 in “Pediatria i Medycyna Rodzinna” This research re-analyzed single-cell gene expression data from a mouse model, confirming that certain genes involved in the EDA-EDAR and WNT pathways are crucial for skin appendage development, suggesting that their restoration may mitigate the effects of hypohidrotic ectodermal dysplasia in children.
March 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that auxin regulates reactive oxygen species-mediated root hair growth by activating transcription factors and enzymes that affect cell elongation.
184 citations
,
December 2018 in “Nature Communications” This study demonstrated that enhancing human skin constructs with hair follicles through engineered cell organization and vascularization improved hair growth in immunodeficient mice, suggesting potential advances for treating alopecia and chronic wounds.
101 citations
,
August 2010 in “PLoS ONE” In this mouse study, severe selenoprotein deficiency in epidermal cells was linked to skin abnormalities, disrupted hair follicle development, and progressive alopecia, highlighting the role of selenoproteins in skin and hair health.
64 citations
,
July 2016 in “Journal of Immunology” In this study, blocking the CXCR3 receptor in mice prevented the development of alopecia areata by inhibiting the accumulation of specific T cells in the skin, suggesting a potential therapeutic approach for humans.
48 citations
,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified chemokine receptor ligands cxcl10 and cxcl11 as new hair-specific transcriptional targets of the Eda pathway, suggesting chemokine signaling plays a role in primary hair follicle patterning.
21 citations
,
April 2010 in “Veterinary Dermatology” This study documented the progression of exfoliative cutaneous lupus erythematosus in German shorthaired pointers and found generally poor responses to therapies, including immunomodulatory drugs and a TNF-α inhibitor.
17 citations
,
December 2006 in “Gene Expression Patterns” This study reports that the mouse Scube3 gene is expressed in various tissues during embryonic development, including the neural tube, limb buds, developing tooth, hair follicle, and skeletal regions.
9 citations
,
January 2010 in “Journal of the Korean Association of Oral and Maxillofacial Surgeons” This study found that stem cells derived from root apical papilla in extracted wisdom teeth demonstrated the strongest potential for osteogenic differentiation compared to those from dental pulp and dental follicle.
5 citations
,
March 2019 in “Scientific Reports” This study reports that the side population technique can isolate melanocyte stem cells from human hair follicles, potentially allowing them to be used for skin pigmentation repopulation.
4 citations
,
April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
January 2025 in “The Pharma Innovation” This paper emphasizes the significant role of millets in promoting environmental sustainability, nutritional security, and economic viability for Indian farmers, while also highlighting the need to increase millet consumption in India to address changing dietary preferences and lack of awareness.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this mouse study, the absence of the Ascl4 gene did not affect the development of hair follicles, teeth, or mammary glands, suggesting it is non-essential for these processes.
November 2011 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” This study found that Polyomavirus A2 infection in mice led to the development of pilomatricomas in hair follicles, with the virus replicating initially in the skin and later infecting matrix cells.
6 citations
,
June 2024 in “Scientific Reports” This study introduced RoPod, a customizable tool for low-stress live imaging of Arabidopsis roots, which improves data reproducibility and provides new insights into plant autophagy by revealing detailed, cell type-specific responses to chemical modulators.
106 citations
,
September 2010 in “Stem cells” This study found that skin-derived precursor cells in mice can originate from both neural crest and somite lineages but show functional similarities regardless of their developmental origins.
23 citations
,
May 2005 in “British Journal of Cancer” This study reported the feasibility of detecting six cell-cycle-related nuclear markers in plucked human scalp and eyebrow hair, providing valuable insights for future intervention studies.
5 citations
,
May 2025 in “Scientific Reports” This study found that extracts from Indian gooseberry leaves showed strong antimalarial activity against Plasmodium falciparum, with low cytotoxicity, suggesting potential for developing new antimalarial drugs.
2 citations
,
September 2023 in “Aging” In this study, researchers found that Elastic Net DNA methylation clocks are not accurate for distinguishing between individuals or identifying health markers, but measuring biological "noise" in stable cytosines may serve as a potential biomarker of aging and disease.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.