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The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

A gene network led by RSL4 is crucial for early root hair growth in response to cold in Arabidopsis thaliana.

A3B5 can reduce skin pigmentation and slow melanoma growth.

Foxn1 gene regulation is crucial for thymus development but not for hair growth.

Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.

The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.

Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

Follistatin helps hair growth and cycling, while activin prevents it.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Specific genes influence hair and cashmere growth in Laiwu black goats.

Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

People with chronic Hepatitis C often have skin problems like itching and contact dermatitis, especially older individuals and women.

Bovine milk-derived exosomes may improve skin, hair, gut, brain, and bone health.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.