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research Medical Hair Restoration Brings REVVup to HairLossSpecialists
This article introduces REVVup Hair Therapy as an alternative to surgery for early-stage hair loss but reports no new clinical findings.
research 197 A novel splice site mutation in LIPH identified in a Japanese patient with autosomal recessive woolly hair
This case report identifies a novel LIPH gene mutation linked to autosomal recessive woolly hair/hypotrichosis in a Japanese boy, expanding the spectrum of known mutations associated with this condition.
research How I Do It: Ahmad’s NPRT System: A New Classification System for Documenting Male Pattern Baldness
This article proposes enhancing the Norwood-Hamilton scale for assessing hair loss patterns but reports no new clinical results.
research Molecular studies of Hutchinson-Gilford progeria syndrome
In this study, a transgenic mouse model suggested that suppressing the expression of the HGPS mutation may reverse disease symptoms, including skin abnormalities, supporting the potential for treatment development.
research ISHRS Best Practices Survey Project MODULE: Anesthesia and Emergency SUMMARY ANALYSIS
This project by the International Society of Hair Restoration Surgery aims to define best practices in hair restoration surgery but does not report new clinical findings.
research Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function
Hairless protein helps control hair growth by regulating vitamin D receptor activity.
research Twins with psychiatric features and a nonsense HRAS variant affecting transcript processing
In this study, researchers observed that twins with a novel de novo nonsense variant in HRAS exhibited distinctive features, including neuropsychiatric symptoms, potentially indicating a wider clinical spectrum for conditions known as RASopathies.
research Parry-Romberg Syndrome Augmented by Hyaluronic Acid Filler
In this first reported case, a 42-year-old female with Parry Romberg Syndrome was treated using hyaluronic acid filler, which the authors suggest may serve as a safe, simple, and cost-effective alternative to more complex surgical methods.
research Simultaneous determination of multi-class active pharmaceutical ingredients by UHPLC-HRMS
This study utilized a UHPLC-HRMS method to identify eight active pharmaceutical ingredients, such as ketoconazole and minoxidil, in 26 out of 100 analyzed cosmetic products.
research 안드로겐 탈모증 환자에서 HDMHG0401-10의 탈모방지, 양모 효과 및 안전성 평가를 위한 임상시험
This article reviews approved treatments for androgenetic alopecia and reports no new research findings, highlighting the need for further studies.
research Disease causing homozygous variants in the human hairless gene
In this study, researchers identified a novel and two previously reported pathogenic mutations in the HR gene associated with atrichia with papular lesions in five Pakistani families.
research 518 Nutrient and stress sensing as novel physiological regulator of human hair pigmentation and greying: Role of mTORC1 activity
In this study, rapamycin was found to increase hair follicle pigmentation and prolong anagen duration in cultured human scalp hair follicles, suggesting it could be explored as an anti-greying agent.
research Atrichia with papular lesions resulting from a novel insertion mutation in the human hairless gene
This study identified a novel insertion mutation in the hairless gene that may contribute to the development of congenital atrichia with papular lesions in a Pakistani family.
research Correspondence
RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
research Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle
This study concluded that the hairless protein interacts with the vitamin D receptor to repress transcription crucial for hair cycling, employing multiple protein interfaces and modulating chromatin structure.
research Hereditary Vitamin D Resistant Rickets: Clinical, Laboratory, and Genetic Characteristics of 2 Iranian Siblings
This study described the clinical and genetic features of two Iranian siblings with hereditary vitamin D resistant rickets, identifying a specific VDR gene mutation contributing to their symptoms.
research 1310 Anti-aging effects of retinoid hydroxypinacolone retinoate on skin models
This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.
research ABHRS President’s Corner
This source describes the American Board of Hair Restoration Surgery's mission to set standards and evaluate skills in hair restoration surgery, but does not report any specific study results.
research High‐Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp–Hodgkin Ectodermal Dysplasia
This report describes two cases of Rapp–Hodgkin ectodermal dysplasia where refractory scalp erosions improved significantly with potent topical steroids; it also suggests a potential link between these scalp conditions and erosive pustular dermatosis of the scalp in elderly patients.
research 650 Controlling mTORC1 activity as a novel therapeutic strategy for managing human hair growth and pigmentation
This study found that inhibiting mTORC1 activity with rapamycin significantly increased melanin production and extended hair growth phase in human hair follicles, suggesting potential for managing hair growth and pigmentation disorders.
research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu
A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
research Hutchinson-Gilford progeria syndrome - A brief introduction
This article reviews treatments for progeria, including aspirin, hydrotherapy, and farnesyl transferase inhibitors, but reports no new clinical results.
research A different hair restoration meeting: The WAHRS Live Surgery Workshop and Symposium
This article discusses the formation and goals of the World Association of Hair Replacement Surgeons, focusing on the exchange of advanced hair restoration surgery techniques, without presenting new research findings.
research Autosomal recessive woolly hair/hypotrichosis caused by LIPH mutations: a case report
This study identified compound heterozygous mutations, c.1101del and c.736 T > A, in the LIPH gene responsible for causing autosomal recessive woolly hair in a child, with c.1101del being a novel frameshift mutation.
research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer
This study found that the protein hairless acts as both a corepressor and coactivator of the vitamin D receptor, influencing gene transcription in a ligand-selective manner.
research ABHRS Sets Plans for Coming Year
This article summarizes a meeting of the American Board of Hair Restoration Surgery's Board of Directors to discuss future plans, but does not report new experimental results.
research Dosimetric analysis of the alopecia preventing effect of hippocampus sparing whole brain radiation therapy
This study found that hippocampus sparing whole brain radiation therapy (HS-WBRT) using multi-field intensity modulated radiation therapy prevents alopecia without compromising cognitive function compared to traditional whole brain radiation therapy.
research Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling
This study found that the hairless gene product (Hr) suppresses VDR-mediated gene activation by directly interacting with the vitamin D receptor, potentially affecting hair follicle function.
research Towards Defining the Pathogenesis of the Hairless Phenotype
This study found that mutations in the hairless gene in mice disrupt hair follicle integrity during catagen, leading to baldness due to disintegrating epithelial structures and loss of normal dermal papilla.