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Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

New genetic locations explain much of hair color variation in Europeans.

Vitamin D and its receptor may help prevent skin cancer.

Vitamin D receptor may help protect against UV-induced skin cancer.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

TGM3 is important for skin and hair structure and may help diagnose cancer.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

Certain genes affect udder shape in Holstein cows, important for health and milk production.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Some Chrysanthemum samples from the USA, Europe, and China differ in quality and some contain harmful cadmium.