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The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

New materials help control stem cell growth and specialization for medical applications.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Artificial skin is improving wound healing and shows potential for treating different types of wounds.

Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Special fiber materials boost the healing properties of certain stem cells.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Skin-derived precursors in hair follicles come from different origins but function similarly.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Smart biomaterials that guide tissue repair are key for future medical treatments.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.