89 citations,
November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
118 citations,
January 2013 in “Biomaterials” Keratin from human hair shows promise for medical uses like wound healing and tissue engineering.
110 citations,
April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.
August 2015 in “MOJ proteomics & bioinformatics” ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
517 citations,
February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
28 citations,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
219 citations,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
220 citations,
March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
79 citations,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
15 citations,
January 2023 in “Biomaterials Research” 3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
18 citations,
April 2022 in “Frontiers in bioengineering and biotechnology” Gelatin microspheres with stem cells speed up healing in diabetic wounds.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
Skin stem cells in hair follicles are important for touch sensation.
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
156 citations,
December 2012 in “Cell Stem Cell” TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
2 citations,
August 2023 in “Life” Bioinspired polymers are promising for advanced medical treatments and tissue repair.
43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
1 citations,
January 2019 in “Elsevier eBooks” New scaffold materials help heal severe skin wounds and improve skin regeneration.
88 citations,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
51 citations,
June 2021 in “Signal Transduction and Targeted Therapy” The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
5 citations,
September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
3 citations,
January 2017 in “Stem Cells International” Adult mesenchymal stem cells can help regenerate tissues and are promising for healing bones, wounds, and hair follicles.
1 citations,
January 2016 in “Elsevier eBooks” The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
1 citations,
January 2019 in “Elsevier eBooks” Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
54 citations,
May 2021 in “Chemical Engineering Journal” The developed scaffold effectively treats chronic wounds by promoting healing and preventing infection.
17 citations,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
1 citations,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.