January 2023 in “Food and nutrition sciences” This study observed that a significant majority of participants who used the dietary supplement Nutrifii™ Renew reported improvements in various health outcomes, including sleep and energy, compared to a multivitamin/mineral group.
22 citations
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October 2004 in “Journal of Investigative Dermatology” This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.
14 citations
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July 2016 in “Journal of Endocrinology” This study observed that equine epididymis mainly expresses the type 1 isoform of 5α-reductase and effectively converts progesterone and testosterone to DHP and DHT, while finasteride and dutasteride inhibited this activity.
6 citations
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September 2021 in “AESTHETIC OROFACIAL SCIENCE” This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.
This article discusses the rising use of low-dose oral minoxidil for androgenetic alopecia and mentions common side effects like hypertrichosis, but provides no new clinical findings.
1 citations
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March 2022 in “JAAD case reports” This case report describes a rare occurrence of injection site reactions in a 77-year-old woman with eosinophilic fasciitis using subcutaneous methotrexate, marking the first documented instance in this patient population.
14 citations
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January 2017 in “Annals of Dermatology” In this retrospective study, low-dose methotrexate was observed to be effective and well-tolerated in treating recalcitrant alopecia areata multiplex, achieving complete or near-complete hair regrowth in about 90% of patients despite some experiencing elevated liver enzymes and gastrointestinal discomfort.
February 2025 in “Biomolecules” This study found that activation of RORA significantly promotes the level of autophagy in rat hair follicle stem cells, suggesting a potential target for research on hair follicle development and treatments for conditions like alopecia.
33 citations
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November 1994 in “Archives of Biochemistry and Biophysics” 198 citations
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September 2007 in “Clinics in Dermatology” Radiofrequency devices effectively tighten skin without surgery.
14 citations
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September 2024 in “Cosmetics” This narrative review explores how exosomes and cell culture-conditioned media are becoming key players in the cosmetic industry for skin rejuvenation and prejuvenation, emphasizing their multifunctional topical benefits and potential future applications.
September 2024 in “Open Repository of the University of Porto (University of Porto)” In this report, a participant in a Portuguese pharmacy master's program detailed their six-month internship at Farmácia Queija Ferreira, highlighting their involvement in medication preparation, creating educational resources, and studying drug interactions, including serious cases involving diclofenac and brimonidine.
17 citations
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January 2019 in “Journal of cancer” This study found that the medicinal formula YH0618 may reduce toxicity from the chemotherapy drug doxorubicin, improving side effects like hair loss and organ damage, while maintaining its anti-cancer effects.
1 citations
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April 2025 in “Drug Delivery and Translational Research” 1 citations
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January 2015 in “Sexual Medicine Reviews” This review discusses the management of recurrent ischemic priapism, highlighting that various treatments show differing efficacy and side effect profiles but that more research is needed to refine these strategies.
63 citations
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July 2024 in “Journal of the American Academy of Dermatology” This study found that the oral JAK1/JAK2 inhibitor deuruxolitinib effectively promoted hair regrowth and patient satisfaction in adults with alopecia areata over 24 weeks.
May 2026 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review outlines the evolution and strategies of drug repurposing, highlighting its transformation from accidental discoveries to a predictive, data-driven discipline through the integration of bioinformatics and artificial intelligence, with notable applications during the COVID-19 pandemic.
8 citations
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March 2012 in “Mass spectrometry letters” This study observed that the isotope-dilution GC-MS technique can assess 5α-reductase activity more effectively than conventional methods in rat liver S9 fractions, particularly at low testosterone levels.
May 2018 in “KU ScholarWorks (The University of Kansas)” This study found that in animal models of Tourette syndrome, stress-induced tic-like behaviors and sensorimotor gating deficits were reduced by finasteride, suggesting a role for neurosteroids like allopregnanolone.
2 citations
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September 2024 in “Journal of the American Academy of Dermatology” Deuruxolitinib is generally safe for treating alopecia areata.
29 citations
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September 2020 in “International Journal of Molecular Sciences” This review outlines the current state of freeze-dried platelet-rich plasma (FD-PRP) research, emphasizing its use in wound healing, lumbar fusion, knee conditions, and dentistry, but reports no new clinical findings.
24 citations
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June 2012 in “Journal of Feline Medicine and Surgery” This case report describes three Devon Rex cats with papular dermatitis due to dermatophytosis, which resolved with antifungal treatment.
October 2025 in “International Journal of Cosmetic Science” This study explored the effects of USPlus® DERM, a bioactive fatty acid extract from Serenoa repens, in promoting hair growth and enhancing hair follicle stem cell stemness in an ex vivo setting, showing potential for both 5‐α reductase-dependent and independent hair loss treatments.
April 2026 in “Communications Biology” In this study of Danioninae species, researchers reported that the presence of breeding tubercles on the pectoral fins is conserved in certain species and linked to local androgen conversion, with steroid 5-α-reductase playing a crucial role in their development.
5 citations
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June 2001 in “Annals of Internal Medicine” This report describes a case where rituximab provided durable remission in a patient with refractory aggressive diffuse B-cell lymphoma that was unresponsive to prior chemotherapy.
2 citations
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December 2013 in “Cancer research” In this study, GTx-027, a selective androgen receptor modulator, significantly inhibited tumor growth in certain breast cancer models and showed good tolerance in a Phase II trial with postmenopausal women.
April 2024 in “Vestnik dermatologii i venerologii” This review highlights the diagnostic potential and therapeutic prospects of exosomes, discussing their use in managing chronic immune-mediated skin conditions, alopecia, and wound healing through their capacity to deliver regulatory molecules between cells.
65 citations
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September 1999 in “The Journal of Dermatology” In this study, complete to excellent hair regrowth was observed in 63.3% of patients with extensive alopecia areata treated with biweekly dexamethasone pulses, although mild side effects were frequent.