5α-Reductase Underscores the Development of Pectoral Fin Breeding Tubercles in Zebrafish

April 2026 in “ Communications Biology ”

Zhaopeng Xu, Xin Zeng, Chuchu Zhang, Baichuan Tong, Zheng Dong, Chen Wang, Suhan Liu, Liyan He, Guang Li, Qingming Qu

5α-reductase steroid 5-α-reductase type 2 srd5a2b Dihydrotestosterone DHT androgen metabolism 5-alpha-reductase

Studysummary In this study of Danioninae species, researchers reported that the presence of breeding tubercles on the pectoral fins is conserved in certain species and linked to local androgen conversion, with steroid 5-α-reductase playing a crucial role in their development.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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