research Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth
Wnt ligands, produced by dermal papilla cells, are essential for adult hair growth and regeneration.
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450-480 / 1000+ results research Gene Expression Signatures and ALADIN Score Correlate with Response of Alopecia Areata Patients to Treatment with JAK Inhibitors
The ALADIN score can predict how well patients with alopecia areata will respond to JAK inhibitor treatments.
research Full Thickness Wound Healing in the Lanyu Pig
Full thickness wounds on Lanyu pigs' skin resulted in abnormal skin structure and function due to changes in molecular expression patterns.
research Vitamin D Protection Against Acute UV Damage: A Critical Role of Autophagy in the Skin
Vitamin D can reduce skin inflammation caused by UV rays by enhancing cell "fitness" and skin repair.
research Generation of a Gene Expression Signature for Sebaceous Glands by Transcriptome Comparison of Psoriasis and Sebaceous Hyperplasia
Sebaceous gland atrophy and abnormal function may contribute to hair loss in psoriasis.
research Stromal Re-Organization in Hair Follicle Development and Cancer Suppression
Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
research Chromatin Remodeler Lymphoid-Specific Helicase (Lsh) Is a Critical Determinant Controlling Postnatal Epidermal Growth, Differentiation, and Response to Injury
Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.
research Engrailed-1 Promotes Eccrine Sweat Gland Development in Permissive Environments
The Engrailed-1 gene plays a key role in the development of sweat glands in mice.
research Synthetic Developmental Tissue Engineering of Human Hair Follicles
Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.
research Using MALDI-MSI Analysis to Study Distribution of FOL-005, a Potent, Novel Inhibitor of Human Hair Growth, After Subcutaneous Injection in Mice
FOL-005, a new substance, was found to reduce hair growth without toxicity when injected into skin, suggesting it could be used to treat excessive hair growth.
research Neoplasms Bypass Immune Evasion via Hair Follicle Residence
Neoplasms hide in hair follicles to avoid the immune system.
research Role of Sdf1-Cxcr4 Signaling in Mouse Appendage Regeneration
Mice without the p21 gene can fully regenerate injured ears due to reduced Sdf1 increase and leukocyte recruitment, suggesting new ways to induce tissue regeneration in mammals.
research Is Intrafollicular Autophagy an Essential Mechanism That Permits Human Hair Follicles to Remain in Prolonged Anagen In Vivo?
Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.
research Study of the Impact of SKPs' Secreted Factors and a Botanical Extract Derived from Jasmine on Keratinocyte Growth and Reconstructed Human Epidermis Thickness
Jasmine extract helps skin cell growth and makes artificial skin thicker, especially when used with skin-derived precursors.
research Adipocyte Stem Cells Are Maintained by PDGFα Signaling in the Skin
Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
research Laminin-511 Is a New Player in the Development of Psoriasis and Controlled via Cannabinoid Receptor Type 1
Laminin-511 is involved in psoriasis development and can be regulated by cannabinoid receptor type 1.
research Identification of a Specific Subset of Monocytes/Macrophages That Coordinates Skin Wound Healing
A specific type of immune cells, called CD301b-expressing macrophages, are crucial for skin repair processes.
research MIG6 Is MEK-Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma
Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.
research UVB Irradiation with Anti-CD154 Antibody Prolonged the Survival of Hair Follicle Allografts in Humanized Mice
Combining UVB irradiation and anti-CD154 antibody improves hair follicle transplant survival.
research Retinoid Induced Changes in the Fatty Acid Profile of Sebum and Its Effect on Bacterial Growth
Retinoids change the fat content in skin oil and reduce bacteria growth, helping to treat acne.
research Ablation of Alkaline Phosphatase in Human Dermal Papilla Spheroid Impairs Hair Follicle Induction
Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
research MEK and BRAF Inhibitors Augment the Production and Accumulation of Sebum in Hamster Sebocytes
MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.
research Safety Data of Four Treatment Regimens in Early Rheumatoid Arthritis Patients
All four treatments for early rheumatoid arthritis had similar and mostly mild side effects.
research PLOS Science Wednesday: Hi Reddit, I'm Zhengquan Yu, Here to Talk About My Recent PLOS Genetics Paper That Has Identified the Key Role of a MicroRNA in Hair Loss. I'm Joined by Maksim Plikus, Who Studies
MicroRNA miR-22 causes hair loss by making hair follicles regress early.
research SP0227 Case 1 Presentation: Arthritis, Lupus and More. Rhupus or Polyautoimmunity?
Managing multiple autoimmune diseases in one patient is very challenging.
research Fever, Maculopapular Rash, and Severe Aphthous Stomatitis in a Renal Transplant Patient
The patient improved after antiviral treatment for a viral infection.
research Testosterone-Secreting Tumor or Insulin Resistance? Metformin as a Diagnostic and Therapeutic Trial
Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
research Assessment and Management of SLE in a Nurse-Led Clinic
Specialist nurses play a crucial role in managing lupus and empowering patients.
research Prevention of Murine Sclerodermatous Chronic Graft-Versus-Host Disease by Rapamycin
Rapamycin increased survival in mice with severe chronic graft-versus-host disease by expanding regulatory T cells.
research Clinical Snippets: Dermatological Studies and Findings
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.