PLOS Science Wednesday: Hi Reddit, I'm Zhengquan Yu, Here to Talk About My Recent PLOS Genetics Paper That Has Identified the Key Role of a MicroRNA in Hair Loss. I'm Joined by Maksim Plikus, Who Studies

September 2015

PLOSScienceWednesday, r/Science

TLDR MicroRNA miR-22 causes hair loss by making hair follicles regress early.

Zhengquan Yu and Maksim Plikus discussed their research on the role of microRNA miR-22 in hair loss, published in PLOS Genetics. Their study demonstrated that miR-22 is crucial in regulating the regression of mouse hair follicles, with increased levels leading to premature follicle regression and hair loss. This research emphasized the importance of understanding the microRNA regulatory network in hair cycling and its implications for hair loss pathology.

View this study on authorea.com →

Discuss this study in the Community →

3 / 3 results

research Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle

24 citations , November 2013 in “Trends in pharmacological sciences”

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations , February 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Towards a Molecular Understanding of Hair Loss and Its Treatment

236 citations , July 2001 in “Trends in Molecular Medicine”

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.