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Microscopic delivery system that sends growth-promoting signals to hair follicles
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an anticonvulsant repurposed for hair loss via histone inhibition
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mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
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research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A
Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
research P53 Involvement in the Control of Murine Hair Follicle Regression
The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
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5 / 1000+ resultscommunity Tretinoin potentially can make hair loss worse ?
Tretinoin may worsen hair loss by inducing premature hair follicle regression. It can be used with minoxidil to increase absorption but should not be used alone.
community Dutasteride 1 year regression. Depressing. (With pictures for proof)
A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.
community Switched from topical to oral finasteride and slowly Withdrawal my hairs from topical minoxidil, and added xl hair serum.
The user switched from topical to oral finasteride, reduced their use of topical minoxidil, and started using XL hair serum with a mesogun injector. They are seeing hair regrowth even with a lowered dose of minoxidil and are considering oral minoxidil for the future.
community 6 months on topical dut (album linked)
The post and conversation are about a user's 6-month progress using topical dutasteride, 8% minoxidil, tretinoin, 2% ketoconazole shampoo, microneedling, oral finasteride, pumpkin seed oil, Vitamin D3, a men's multivitamin, rosemary oil, and 5% minoxidil foam for hair loss treatment.
community Did anyone's hairline get permanently destroyed by dutasteride?
User asks if dutasteride destroys hairlines. Some users share negative experiences, while others report improvement or no issues. Advice given: start with finasteride and consider anti-androgens if needed.