research Dynein Is Involved in the Movement, Distribution, Acidity, and Transfer of Melanosomes
Dynlt3 is important for melanosome transport and skin coloration.
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research Environmental Pathobiology of Frontal Fibrosing Alopecia: Does Linalool Promote FFA Development and Progression?
Linalool in personal care products may contribute to hair loss by damaging hair follicle stem cells and triggering harmful immune responses.
research Ultrasound Examination of Subcutaneous Nodules in Dermatology
Ultrasound is a useful, safe, and affordable tool for diagnosing and managing skin nodules.
research Efficacy and Safety of Topical KX-826 in Male Subjects with Androgenetic Alopecia: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Study
KX-826 is safe and effectively increases hair count in men with hair loss.
research Neuroendocrinology of Human Scalp Hair Follicles: Growth Hormone-Releasing Hormone Stimulates Hair Growth and Controls a Fully Functional Intrafollicular Hypothalamic-Pituitary-Somatotropic Signaling Axis
Growth hormone-releasing hormone (GHRH) boosts hair growth and human scalp hair follicles have their own growth hormone system.
research Exploring the Relationship Between Acne and Mental Health
Acne is genetically linked to a higher risk of depression, anxiety, schizophrenia, and bipolar disorder, with the strongest link to bipolar disorder.
research Three-Dimensional Culture of Dermal Papilla Cells Improves Their In Vitro Angiogenic Activity
Growing dermal papilla cells in 3D improves their ability to help form new blood vessels.
research Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Affect Stem Cells in Human Scalp Hair Follicles
Fish-derived collagen may help hair grow longer and affect hair stem cells, while bovine collagen could benefit hair stem cell maintenance, potentially aiding in hair loss conditions.
research Targeting JAK/STAT and Wnt/Beta-Catenin Pathways and 5-Alpha-Reductase Activity to Develop an Effective Anti-Hair Loss Product
The lotion with specific plant extracts effectively increased hair growth and improved hair cycle in subjects after 3 months.
research CsA-Induced Hypertrichosis Might Be Caused in Part by Inhibition of TGF-β2 Expression in Dermal Papilla Cells
The medicine Cyclosporin A might cause excessive hair growth by reducing a protein that controls hair growth.
research Psychological Stress and Cognitive Function in COVID-19 Induced Telogen Effluvium Patients
COVID-19 patients with hair loss experienced greater cognitive deficits and more symptoms of depression, anxiety, and stress.
research The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles
Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
research Nutrient and Stress Sensing as Novel Physiological Regulator of Human Hair Pigmentation and Greying: Role of mTORC1 Activity
Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.
research Skin Organoids Derived From NCSTN Mutated Patient-Induced Pluripotent Stem Cells Recapitulate Hidradenitis Suppurativa Pathogenic Hallmarks
Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
research DermaCult Keratinocyte Expansion Medium: A Serum- and BPE-Free Medium Supporting Long-Term Feeder-Free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes
DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
research Deciphering Pathomechanisms in Solar Urticaria
The study found that skin inflammation and immune response pathways are activated in Solar Urticaria patients after UV exposure, unlike in healthy people.
research Regulation of the Lipidome and Lipid Metabolism in Prematurely Senescent Human Dermal Fibroblasts
Aging skin cells change their lipid profiles due to stress, affecting skin health.
research Integrated Single-Cell Chromatin and Transcriptomic Analyses of Human Scalp Reveal Etiological Insights Into Genetic Risk for Hair and Skin Disease
The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.
research Oncogenic Kras Induces Spatiotemporally Specific Tissue Deformation Through Converting Pulsatile Into Sustained ERK Activation
The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.
research Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion Through Enhancer Dynamics
Removing Mediator 1 causes teeth cells to turn into hair cells.
research Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle
Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.
research Induction of Type 17 Collagen Decreases Ultraviolet B-Induced Cellular Senescence in Human hTert/KER-CT Keratinocytes
Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.
research Physiological Function of Krox20 (Egr2) in Epithelial Stem Cells
Krox20 is important for maintaining stem cells in the skin and affects hair growth and color.
research Dermal Fibroblast Expression of LEF1 Is Critical to Normal Skin and Hair Development and Regenerative Wound Healing in Mice
Lef1 is essential for normal skin, hair growth, and healing wounds in mice.
research Guiding Skin Organoid Generation via Extracellular Matrix Cues and Spatially Controlled Morphogen Gradients
Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
research Characterization of Cutaneous Hormone Production Through Analysis of Skin Secretions
Skin produces different hormones depending on body part and sex, and a new method can measure them.
research Exosome Therapy in Hair Regeneration: A Literature Review of the Evidence, Challenges, and Future Opportunities
Exosome therapy shows promise for hair loss but needs more research on safety and effectiveness.
research DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Three-Dimensional Chromatin Topology in Lineage-Specific Loci to Control Hair Growth
Tet2 and Tet3 enzymes are essential for controlling hair growth by affecting DNA demethylation and gene expression in mice.
research Particulate Matter Induces Inflammatory Response in Human Outer Root Sheath Cells via Oxidative Stress-Dependent MAPK and JAK-STAT Signaling Pathways
Particulate matter causes inflammation in hair cells, potentially harming hair growth.
research Impaired Follicular Nrf2 Signaling: Potential Early Therapeutic Target in Hidradenitis Suppurativa
Targeting impaired Nrf2 signaling might help treat hidradenitis suppurativa early on.