Deletion of Hoxc13 in Frogs Reveals Key Steps in the Molecular Evolution of Cornified Skin Appendages

    A.P. Sachslehner, M. Carron, S. Demuynck, E. De Baere, K. Vleminckx, L. Eckhart
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    Studysummary This research suggests that hair keratins evolved from claw keratins in a hairless ancestor, with Hoxc13 controlling their expression in tetrapods, evidenced by the knockout of Hoxc13 hindering claw formation in Xenopus tropicalis frogs.
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