75 citations
,
February 2016 in “The Journal of Sexual Medicine” This review highlights the efficacy of transdermal testosterone therapy in improving sexual function in women with hypoactive sexual desire disorder, though approved formulations and long-term safety data are limited.
75 citations
,
January 2011 in “Plastic and Reconstructive Surgery” This review discusses the use of dermal regeneration templates for treating burn injuries and other wounds, highlighting their effectiveness in reducing scars and aiding in regenerative processes, but reports no new clinical results.
73 citations
,
March 2017 in “Scientific Reports” This study demonstrates that bioengineered tooth germ autologously transplanted in a postnatal canine model can achieve functional tooth restoration, suggesting its potential for future clinical regenerative medicine.
72 citations
,
January 2023 in “International Journal of Biological Sciences” This review discusses recent advances in the therapeutic potential of exosomes for wound healing, highlighting their benefits and challenges but reports no new clinical results.
72 citations
,
April 2008 in “Organogenesis” This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.
72 citations
,
September 1997 in “Dermatologic Surgery” This review discusses follicular transplantation for hair restoration, highlighting the importance of evaluating patient suitability and careful planning to achieve excellent cosmetic outcomes, but reports no new research findings.
71 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews the reported sexual and psychological side effects of 5-alpha reductase inhibitors for benign prostatic hyperplasia, emphasizing the need for further clinical studies.
70 citations
,
April 2013 in “Endocrine” This review found that lifestyle changes, such as diet and exercise, are beneficial for managing metabolic and endocrine abnormalities in obese patients with PCOS and suggests combining these with anti-obesity agents for enhanced effects.
69 citations
,
June 2017 in “Experimental Biology and Medicine” This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.
69 citations
,
December 2016 in “Facial plastic surgery” This review discusses the anatomical and histological characteristics of facial fat compartments and reports no new clinical results, emphasizing a need for further research on their role in facial aging.
69 citations
,
November 2010 in “Middle East Fertility Society Journal” This review discusses the multifactorial origins and pathophysiology of PCOS and highlights the effectiveness of lifestyle modifications as a first-line intervention, reporting no new research results.
68 citations
,
September 2018 in “Trends in Cell Biology” This review discusses the senescence–stemness connection in cellular biology and reports no new findings, highlighting implications for both tissue repair and aggressive cancer behavior.
67 citations
,
June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
67 citations
,
September 1997 in “Dermatologic Surgery” This article explores aesthetic techniques in follicular hair transplantation, emphasizing natural-looking results and plans to present a case study, but it reports no new clinical findings.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
66 citations
,
June 2015 in “Aesthetic Plastic Surgery” This review of 47 studies indicates that platelet preparations may significantly enhance cellular activity, wound healing, and facial aesthetic outcomes in facial plastic surgery, though potential publication bias should be considered.
65 citations
,
February 2017 in “Pflügers Archiv - European Journal of Physiology” This review examines the roles of macrophages and Langerhans cells in skin homeostasis and suggests that understanding these functions can aid in developing therapies for skin and hair regeneration, but it reports no new research findings.
65 citations
,
March 2016 in “Lasers in Medical Science” This review found that many low-level light therapy studies report beneficial effects but often fail to provide adequate measurement details, affecting the reliability and repeatability of the research.
65 citations
,
May 2010 in “Current Women's Health Reviews” This review discusses oxidative stress's role in polycystic ovary syndrome and examines various biomarkers to understand its impact on the disorder's pathogenesis, but reports no new clinical results.
64 citations
,
January 2009 in “Gynecological Endocrinology” This study found that myo-inositol treatment reduced hirsutism and acne in women with PCOS by improving their metabolic profiles, including lower insulin and testosterone levels.
61 citations
,
January 2015 in “Hormones” In this study, short-term liraglutide treatment led to significant weight loss in obese women with newly diagnosed PCOS and a higher metabolic risk profile compared to metformin.
60 citations
,
July 2020 in “ACS Nano” This review discusses the progress and challenges in delivering CRISPR/Cas9 systems for in vivo genome editing, highlighting current methods and opportunities for future therapeutic applications.
60 citations
,
June 2019 in “Ageing Research Reviews” This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.
60 citations
,
September 2015 in “Expert Review of Clinical Immunology” This study suggests that CD8+ cytotoxic T lymphocytes play a crucial role in the development of alopecia areata, based on observations in rodent models that mimic human autoimmune disease.
60 citations
,
October 2014 in “Journal of the American Academy of Dermatology” This review examines the definition, etiology, pathogenesis, and clinical features of polycystic ovary syndrome but reports no new clinical findings.
60 citations
,
February 2010 in “Gynecological Endocrinology” This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.
59 citations
,
June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
59 citations
,
January 2010 in “Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review” This article reviews the medicinal properties of Semecarpus anacardium and its biologically active compounds, but it reports no new clinical results.
59 citations
,
September 2008 in “Experimental dermatology” This study reports that C3H/HeJ mice and DEBR rats serve as effective models for screening potential treatments for human alopecia areata, despite certain challenges in predictability and cost.
58 citations
,
January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.