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This study found that targeting IL-17 signaling in aged skin reduces inflammation and delays age-related traits, suggesting a potential strategy to prevent age-associated skin ailments.

This study reports that a novel gain-of-function mutation in TMEM173, combined with polymorphisms in TMEM173 and IFIH1, results in a distinct clinical phenotype with features of SAVI, including alopecia and photosensitivity.

This study suggests that a specific subpopulation of umbilical cord-derived mesenchymal stem cells, CMD, may enhance wound healing and tissue quality in chronic skin ulcers, with promising results in both murine and equine models.

This study found that lysine carboxymethyl cysteinate helps protect the epidermis from UVB-induced damage by activating autophagy and restoring cornification processes in a skin model.

In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.

This report details a case study where a 40-year-old woman experienced allergic contact dermatitis and angioedema-like symptoms after using PPD-containing hair dye. Patch testing confirmed a positive reaction to PPD, highlighting the substance's potential to cause both T-cell and IgE-mediated hypersensitivity reactions.

In this review, summarized findings suggest that emerging targeted immunotherapies may offer promising treatment options for alopecia areata by addressing the breakdown of hair follicle immune privilege.

This study reviews current research on skin repair and regeneration, highlighting promising methods such as stem cell therapies, nanotechnology, and skin substitutes, which may enhance healing and resistance to environmental damage.

CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.

This study observed that extracellular matrix scaffold membranes performed less effectively in wound healing for aged mice compared to younger ones, with senescent SPP1+ macrophages potentially hindering epidermal and fibroblast repair abilities.

This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.

In this review, researchers discussed the anti-inflammatory and immunomodulatory properties of metformin and hypothesized that its topical application could benefit those with alopecia areata, given its effects on immune pathways, hair regrowth, and autoimmune disease management.

In this study, researchers used spatial transcriptome profiling to identify immune disturbances in the peri-infundibular region of androgenetic alopecia patients’ hair follicles, finding increased CD4+ T cells with a bias toward Th2 immune responses compared to controls.

In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.

This review discusses the complexity of identifying hair follicle antigens involved in alopecia areata and reports no new clinical results, emphasizing the need for further research on autoantigen identity.

This study suggests that autophagy is essential for regulating TLR3-mediated regenerative processes in human keratinocytes.

This source evaluates the clinical effectiveness of 308 nm monochromatic excimer phototherapy in treating moderate-to-severe alopecia areata, noting that both laser and lamp methods show promise without significant risks.

This study suggests that varicella-zoster virus infection in skin cells may play a role in segmental vitiligo's progression and depigmentation.

This study found that type 2 immunity, especially involving ILC2 cells, helps maintain skin homeostasis by regulating the proliferation and community stability of hair follicle epithelial cells in the presence of Demodex mites.

This study found a specific T cell receptor that may be key in carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis, suggesting potential therapeutic targets.

This study evaluated interleukin-26's antimicrobial activity in Hidradenitis Suppurativa and explored its potential role in chronic skin inflammation.

In this study, CTCF was found to play essential roles in epidermal differentiation and skin barrier formation, simultaneously acting as a suppressor of epithelial inflammatory responses in mouse skin.

This study found that a single high dose of oral vitamin D reduced UV-induced skin erythema and inflammation in humans by enhancing autophagy, suggesting new clinical avenues for skin repair.

This review discusses the potential pathogenic mechanisms of cicatricial alopecia and emphasizes the need for further research on treatment methods, but it reports no new clinical findings.

In this study, researchers observed that TLR3 and scavenger receptors play key roles in skin barrier repair following UVB damage, contributing to our understanding of cellular responses to skin injury.

This study observed that Platycarya strobilacea S. et Z. extract enhanced hair growth and improved hair follicle length and immune response in mice compared to control groups.

This article discusses the inflammation process in dissecting cellulitis and folliculitis keloidalis, noting the role of follicular rupture and hair fragments while reporting no new results; the authors highlight differences in bacterial presence and pathogenesis understanding.

This article reviews topical agents for cosmetic surgery and reports no new clinical results; it emphasizes the importance of skin preparation and management for optimal surgical outcomes.

This study found that fermented red ginseng marc alleviated skin lesions, reduced inflammation, and demonstrated antioxidant effects in an AD-like mouse model, suggesting potential therapeutic applications for atopic dermatitis.

This study found that electrospinning membranes with smaller fiber diameters significantly improved skin wound healing by promoting cell proliferation and encouraging reparative macrophage transformation.