Current Aspects of Skin Reparative Regeneration: A Modern Perspective on the Problem

The document discusses the challenges and advancements in the field of skin reparative regeneration, emphasizing the impact of environmental factors such as trauma, radiation, and chemicals on skin health. It highlights the importance of studying the structural and physiological aspects of skin regeneration due to the high incidence of skin injuries and the limitations of current healing methods. Key areas of research include the use of stem cells and their derivatives, nanotechnology, and the development of skin substitutes. The positive effects of selenium and copper compounds on skin resistance are noted. The use of mesenchymal and adipose-derived stem cells is shown to promote angiogenesis, inflammation processes, immune response, cell proliferation, and re-epithelialization. Future directions involve creating bioengineered skin substitutes with appropriate morphophysiological characteristics and improving wound treatment methods to prevent fibrous scar development.