16 citations
,
February 2018 in “BMC Genomics” This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.
11 citations
,
April 2013 in “Hormones” This article reviews recent data suggesting that metformin may be beneficial for anovulatory PCOS patients with normal BMI and clomiphene resistance but emphasizes that more studies are needed to confirm these findings.
1 citations
,
June 2012 in “Springer eBooks” This article discusses the potential of acupuncture as a complementary or alternative therapy for PCOS, highlighting experimental evidence of its positive effects on reproductive and metabolic function, but reports no new clinical results.
This review examines the potential of Parquetina nigrescens for managing Polyendocrine Metabolic Ovarian Syndrome, emphasizing its pharmacological activities and highlighting its promise as an affordable complementary therapy.
June 2023 in “Journal of Ayurvedic and herbal medicine” This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.
December 2023 in “Anti-Aging Eastern Europe” This review discusses the interplay between polycystic ovary syndrome, aging, and fertility in women, and reports no new clinical results; the authors highlight pathways and interventions needing further research.
25 citations
,
July 2013 in “Environmental Toxicology and Chemistry” This study found that spironolactone reduced fish fecundity and caused masculinization of females at certain concentrations, while having no effect on Daphnia magna reproduction, underscoring concerns for environmental exposure to vertebrates.
16 citations
,
May 2019 in “International Journal of Women's Dermatology” This study reviewed and categorized dermatological drugs for pregnancy and lactation according to new FDA labeling guidelines, which replaced simplistic letter categories with detailed information, aiming to improve prescribing decisions by addressing both maternal and paternal reproductive potential.
11 citations
,
December 2016 in “Frontiers in Psychology” In this study, researchers used computer-generated models to demonstrate that subtle changes in hair diameter, density, and style significantly affect perceptions of age, health, and attractiveness.
17 citations
,
May 2021 in “Journal of Assisted Reproduction and Genetics” This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
3 citations
,
April 2020 in “Journal of Mind and Medical Sciences” This review discusses the reproductive challenges and potential pathophysiological mechanisms related to anorexia nervosa, noting possible long-term effects on fertility and pregnancy outcomes.
2 citations
,
July 2024 in “Cureus” This review discusses the potential benefits of using autologous endometrial cells and PRP via hysteroscopic injections to improve pregnancy outcomes in ART, particularly in individuals with refractory thin endometrium, but reports no new clinical results.
1 citations
,
October 2023 in “International Journal of Ayurvedic Medicine” This article discusses the potential benefits of decade-wise Rasayana therapy in enhancing female reproductive health by addressing various life stages, from pre-menarche to post-menopause, and draws from traditional and contemporary sources to conceptualize its importance.
4 citations
,
October 2023 in “Fertility and Sterility” This review highlights potential negative impacts of certain medications on male fertility, such as hormonal disruption and germ cell toxicity, emphasizing the importance of clinicians being aware of these effects to advise on safer alternatives.
February 2023 in “Vaccines” This review discusses the potential impact of COVID-19 on the male reproductive system and highlights unanswered questions regarding its mechanisms and implications for men's health and fertility, reporting no new clinical results.
7 citations
,
May 2023 in “Nanomaterials” In this study on Danio rerio, researchers found that exposure to titanium dioxide nanoparticles did not affect embryonic development but altered the structure of male gonads, acting as potential endocrine disruptors with androgenic activity.
5 citations
,
May 2023 in “Science of the total environment” This study observed that higher PFAS concentrations during adolescence were linked to later pubertal development and lower estradiol levels in females, but not in males, potentially due to PFAS excretion with menstrual fluid.
December 2023 in “Migration letters” This meta-analysis reviewed 25 studies and suggested that herbal interventions could improve reproductive health in women with PCOS, showing benefits across measures such as Body Mass Index, hirsutism, and insulin levels, although results were mixed for fasting glucose and FSH levels.
January 2025 in “American Journal of Medical and Clinical Research & Reviews” In this literature review, potential health risks of toxic chemicals commonly found in cosmetic products were linked to issues such as cancer, reproductive abnormalities, and skin diseases, highlighting concerns over ingredients like talc, parabens, and phthalates.
3 citations
,
January 1993 in “Toxicological Sciences” This study found that 2-ethylhexanoic acid impaired fertility in Wistar rats and delayed postnatal development of pups, suggesting potential reproductive toxicity at certain dosages.
27 citations
,
May 2002 in “The Journal of Clinical Endocrinology & Metabolism” This study found that brothers of women with PCOS exhibit elevated DHEAS levels, indicating a potential familial genetic trait, but did not show increased rates of premature balding.
21 citations
,
December 2007 in “Primary Care” This article reviews the challenges in treating PCOS, noting the potential benefits of insulin sensitizers on ovulatory function and pregnancy outcomes, and calls for more long-term studies on metabolic interventions.
15 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the effects of 5ARI drugs on male reproductive parameters, reporting potential decreases in sperm count and motility more significantly in men with pre-existing oligozoospermia, but does not provide fertility outcomes.
May 2026 in “Reviews in Endocrine and Metabolic Disorders” This review explores weight loss interventions during gestation, emphasizing incretin-based therapies' potential to enhance reproductive health and address metabolic changes for better maternal and fetal outcomes.
5 citations
,
January 2019 in “cIRcle (University of British Columbia)” This research observed that women with PCOS may improve insulin resistance and reduce hyperandrogenism by increasing fiber and magnesium intake, and face higher anxiety symptoms potentially linked to societal appearance expectations.
26 citations
,
September 2005 in “Pharmacology Biochemistry and Behavior” This study found that inhibiting the 5alpha-reductase 2 pathway in male rats affects brain sexual differentiation and leads to reproductive changes, including increased pre-implantation loss despite unchanged copulatory potential.
5 citations
,
December 2015 in “Asian pacific Journal of Tropical Biomedicine” In this study, the aqueous extract from Phthirusa pyrifolia leaves significantly decreased testosterone levels in male Wistar rats without causing liver or kidney damage, suggesting potential effects on libido and reproduction.
4 citations
,
October 2022 in “Evidence-based complementary and alternative medicine” This study found that Ficus carica extract enhanced fertility markers, including hormone levels and reproductive organ activity, in rats of both sexes, suggesting potential benefits for managing fertility issues.
This study investigated the epigenetic effects of finasteride on reproductive signaling pathways using Sertoli cell models and found that finasteride exposure led to altered epigenetic profiles in multiple genes, including ESR1 and DNMT3A, indicating potential impacts on reproductive-related pathways.
19 citations
,
January 2023 in “Genes” This study identified genomic regions and genes associated with wool, live weight, body condition, and reproduction traits in Uruguayan Merino sheep, highlighting potential genetic factors influencing these characteristics.