March 2026 in “Journal of Nanobiotechnology” This study developed a hydrogel microneedle system combining ginseng-derived exosomes and biomimetic nanoparticles to address oxidative stress, inflammation, and melanocyte deficiency in vitiligo, showing significant repigmentation in mice within 3 weeks by enhancing melanocyte protection and keratinocyte proliferation.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study by Refat et al. found that the level of CD8+ T cell infiltrates in vitiligo lesions before surgical treatment can predict the likelihood of successful repigmentation, suggesting a potential new method for identifying patients who may benefit the most from surgical interventions.
October 2022 in “Journal of advances in medicine and medical research” This study found that low-level laser therapy combined with NB-UVB therapy led to improvement in re-pigmentation for many stable vitiligo patients, with minimal and transient side effects.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” This article discusses the advances in understanding wound-induced hair follicle neogenesis (WIHN) and highlights the roles of specific signaling pathways and cellular plasticity, noting no clinical results but suggesting potential areas for further research.
15 citations
,
June 2021 in “International Journal of Molecular Sciences” This study demonstrated that novel curcumin analogs CMC2.24, CMC2.23, and CMC2.5 were more effective and less toxic than parent curcumin in inhibiting melanin production in normally pigmented human melanocytes, suggesting potential for skin depigmentation therapies.
10 citations
,
September 2018 in “Regenerative Medicine” This review explores the mechanism and potential applications of wound-induced hair follicle neogenesis but reports no new clinical results, highlighting the need for further research in hair regeneration therapies.
3 citations
,
January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
August 2026 in “Molecules” This review discusses key molecular targets in cosmetic research and reports no clinical results; it highlights the role of telomerase, sirtuins, and tyrosinase in anti-aging and depigmentation strategies.
September 2010 in “Companion Animal” This article reviews a clinician's approach to diagnosing and managing canine alopecia and reports no new clinical findings.
1113 citations
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August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
63 citations
,
December 2002 in “Archives of Dermatology” This abstract contains no research results; it provides information about the JAMA Dermatology journal and its access options.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” This article discusses the role of neurohormones and neuropeptides in hair follicle pigmentation and outlines promising neuroendocrinological strategies to address greying and damage, but reports no new clinical results.
2 citations
,
June 2001 in “American Journal of Pathology” This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.
2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” This article reviews the need for multicenter clinical trials to establish reference data for ultrasound screening protocols for Down syndrome and reports no new findings.
1 citations
,
November 2025 in “Clinical and Experimental Medicine” This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
This case study reports a rare co-occurrence of alopecia areata and vitiligo in a 13-year-old female, suggesting a potential pathogenic link between the two autoimmune skin diseases.
January 2012 in “Postgraduate obstetrics & gynecology” This descriptive abstract provides information about a continuing medical education activity for physicians, designating 1.5 credits for participation, but reports no new research findings.
This study found clinical markers like leukotrichia and trichrome lesions in non-segmental vitiligo patients were linked to greater disease extent and poor response to treatment.
170 citations
,
December 2009 in “Histopathology” This review discusses the histopathological diagnosis of scarring and non-scarring alopecias, emphasizing the importance of adequate tissue sampling and clinical information; it reports no new empirical results.
23 citations
,
April 2002 in “Journal of the American Academy of Dermatology” This case report describes persistent depigmented hair regrowth from an alopecia areata patch, challenging the previous assumption that such regrowth is only temporary.
1 citations
,
June 2013 in “Semina Ciências Agrárias” This study found that although soil and forage in Middle Paraíba, Brazil, contained normal to high copper levels, the surrounding bovine populations showed signs of copper deficiency likely due to antagonistic effects from high iron, zinc, and manganese levels.
This chapter provides an overview of terminology for various skin lesions, including primary and secondary types, but does not report new findings or results.
In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.
December 2025 in “Revista Científica Sinapsis” This study highlights the need for personalized hair care plans based on scalp type and environmental factors, underscoring the importance of targeted product selection and the involvement of professionals to create effective solutions for modern lifestyle issues.
210 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses the role of intrinsic skin signals, rather than serum signals, in regulating melanin synthesis and hair pigmentation, but reports no new experimental data.
109 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
63 citations
,
December 1988 in “International Journal of Dermatology” Vitiligo causes white skin patches and is linked to autoimmune issues.
49 citations
,
August 2007 in “Dermatologic surgery” This review discusses newer therapeutic techniques for treating postacne scarring, highlighting their effectiveness for particular grades of scars, and reports no new clinical results.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” This review suggested that low-level light therapy using red/near-infrared light could be a safe and effective treatment for various skin and hair conditions, though more robust trials are needed to solidify its clinical utility.