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Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

JAK inhibitors are more effective and safer for treating alopecia areata than dupilumab and apremilast.

Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.

Synthetic hair fibers for hair restoration were controversial in 2009 due to health risks and lack of support from the International Society of Hair Restoration.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Dutasteride is the most effective hair loss treatment after 24 weeks, but finasteride leads to the most hair growth after 48 weeks.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.

Dianabol boosts muscle growth but has serious health risks and legal issues.

Skin cancer in sun-exposed areas is more likely to come back.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

People with common hair loss conditions may have a higher risk of heart disease and related health issues.

Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.

People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.

Shorter PSADT after prostate surgery is linked to higher risk of death.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Use finasteride over dutasteride for hair loss; consider topical treatments and weigh risks.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Patients should discuss risks with doctors before using finasteride for hair loss.

Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.

Drinking alcohol before taking flibanserin does not increase the risk of severe low blood pressure or fainting.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.

The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Older skin has higher cancer risk due to inflammation and stem cell issues.