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90-120 / 1000+ results![Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles](/images/research/104cf6c2-d495-4bfd-b9fe-dc77d7c18662/small/2216.jpg)
research Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles
Finasteride potentially treats hair loss by reducing DHT production.
![Antiandrogens and Androgen Inhibitors in Dermatologic Treatments](/images/research/925d19de-8ca0-4d51-99ff-222ace6cb768/small/12037.jpg)
research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
![Treatment Guidelines in Adult Women: Effectiveness of Hormonal Therapy in Treating Acne Vulgaris](/images/research/b06eb2a1-799d-4654-9c34-db8a70ae5246/small/14748.jpg)
research Treatment Guidelines in Adult Women: Effectiveness of Hormonal Therapy in Treating Acne Vulgaris
Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
![Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats](/images/research/c3683642-d37a-4376-bbc7-476940e73d7d/small/18976.jpg)
research Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats
Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
![Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University](/images/research/f8b61378-1122-4670-a535-ccb2020aeb5c/small/16220.jpg)
research Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University
Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.
research Inhibition of 5α-Reductase in the Rat Prostate by Cimicifuga Racemosa
Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.
![Pharmacogenetic Analysis of Human Steroid 5α Reductase Type II: Comparison of Finasteride and Dutasteride](/images/research/480b1f98-d719-4178-af00-8058fb7cc47a/small/2603.jpg)
research Pharmacogenetic Analysis of Human Steroid 5α Reductase Type II: Comparison of Finasteride and Dutasteride
Dutasteride is more efficient than finasteride, but individual results vary.
![Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite](/images/research/3946b99a-8449-435d-8a7e-145cf585ee7f/small/2729.jpg)
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
![Hair Growth-Promoting Effect of Resina Pini and Its Main Constituent, Abietic Acid, in Mouse Model of Alopecia](/images/research/384b0cf8-85c6-454c-8f06-92c42fe54f76/small/20967.jpg)
research Hair Growth-Promoting Effect of Resina Pini and Its Main Constituent, Abietic Acid, in Mouse Model of Alopecia
Pine resin and abietic acid were found to promote hair growth in mice.
research 5α-Reductase Inhibitory Potential of Hibiscus Rosa Sinensis: Effective for the Management of Alopecia
Hibiscus rosa sinensis may help manage hair loss.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Effects of Lespedeza Cuneata Aqueous Extract on Testosterone-Induced Prostatic Hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research Androgenic Alopecia and Dutasteride in Hair Mesotherapy: A Short Review
Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.
![Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal](/images/research/0f5e4fa3-50fe-4b02-aa36-ab9530e4b102/small/16498.jpg)
research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal
Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
research The Many Faces of Calcineurin Inhibitor Toxicity—What the FK?
Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
![Testosterone Metabolite Nonessential For Androgen Effects](/images/research/9b12f6c8-34e5-406e-b2dd-decdb4a34ec1/small/25783.jpg)
research Testosterone Metabolite Nonessential For Androgen Effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
![Health Benefits and Safety of Red Pigmented Rice (Oryza Sativa L.): In Vitro, Cellular, and In Vivo Activities for Hair Growth Promoting Treatment](/images/research/2a683cd5-541a-4a80-9d27-38270d3e13a1/small/22795.jpg)
research Health Benefits and Safety of Red Pigmented Rice (Oryza Sativa L.): In Vitro, Cellular, and In Vivo Activities for Hair Growth Promoting Treatment
Red pigmented rice, like Sang-Yod rice, could help promote hair growth and prevent hair loss.
![New Drugs Under Investigation for the Treatment of Alopecias](/images/research/e1768a16-0d73-4432-ab37-375532a53150/small/15945.jpg)
research New Drugs Under Investigation for the Treatment of Alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
![Triple Hormonal Blockade (ADT3): A Patient’s Perspective](/images/research/4c980127-f606-4008-b9b3-3fd74e7caa9c/small/31846.jpg)
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
![The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease](/images/research/453c2df3-f176-4781-92c8-ee02f485cdbd/small/3661.jpg)
research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
![Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial](/images/research/0511a839-670e-46c9-a59a-15bfc6a22458/small/14597.jpg)
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
![Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase](/images/research/f6a78f52-c8c4-43a6-bf54-5f4b30058b44/small/28685.jpg)
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
![Prolongation of Off-Cycle Interval by Finasteride Is Not Associated with Survival Improvement in Intermittent Androgen Deprivation Therapy in LNCaP Tumor Model](/images/research/0e733897-5222-4b31-acf5-784c4169bf8a/small/2895.jpg)
research Prolongation of Off-Cycle Interval by Finasteride Is Not Associated with Survival Improvement in Intermittent Androgen Deprivation Therapy in LNCaP Tumor Model
Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.
![Steady-State Pharmacokinetics of Oral Testosterone Undecanoate with Concomitant Inhibition of 5α-Reductase by Finasteride](/images/research/0a7b342f-123b-421d-a334-ff5ba2feae3a/small/3100.jpg)
research Steady-State Pharmacokinetics of Oral Testosterone Undecanoate with Concomitant Inhibition of 5α-Reductase by Finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
![Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity](/images/research/32654c6a-0216-4e35-89dc-99a74b0f3852/small/15577.jpg)
research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Urtica Dioica Extract Downregulates the Gene Expression of 5α-Reductase Type II in HaCaT Cells: Possible Implications Against Androgenic Skin Diseases
Urtica dioica extract may help treat androgenic skin diseases by reducing a specific gene's activity.
![Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels](/images/research/31972a10-89f7-4504-99c9-7f07c4318a92/small/15176.jpg)
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
![Anti-Androgenic Activities of the Triterpenoids Fraction of Ganoderma Lucidum](/images/research/b114bdf8-1fc0-4da8-9052-bb61fb08f138/small/15111.jpg)
research Anti-Androgenic Activities of the Triterpenoids Fraction of Ganoderma Lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
![Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility](/images/research/9b2608e4-dd5c-4871-997e-18e3f2d62747/small/15273.jpg)
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.