Health Benefits and Safety of Red Pigmented Rice (Oryza Sativa L.): In Vitro, Cellular, and In Vivo Activities for Hair Growth Promoting Treatment

November 2022 in “ Cosmetics ”

Natthawut Thitipramote, Supapong Imsonpang, Passanesh Sukphopetch, Prinyaporn Pradmeeteekul, Junniphaphorn Nimkamnerd, Witayapan Nantitanon, Wantida Chaiyana

red pigmented rice Oryza sativa Sang-Yod Mun-Poo 5α-reductase inhibition androgenic alopecia dihydrotestosterone hair matrix cells hair growth C3H mice skin irritation red rice black rice SY MP 5-alpha-reductase inhibition DHT hair cells mice

TLDR Red pigmented rice, like Sang-Yod rice, could help promote hair growth and prevent hair loss.

The study "Health Benefits and Safety of Red Pigmented Rice (Oryza sativa L.): In Vitro, Cellular, and In Vivo Activities for Hair Growth Promoting Treatment" found that Thai native red and black pigmented rice extracts, particularly Sang-Yod (SY) and Mun-Poo (MP), have hair growth-promoting properties. The extracts showed in vitro 5α-reductase inhibition, which can help prevent androgenic alopecia by blocking the conversion of testosterone to dihydrotestosterone, a hormone that contributes to hair loss. The extracts also increased the proliferation of human hair matrix cells and promoted extensive hair growth in C3H mice without causing skin irritation. The study concludes that red pigmented rice, especially Sang-Yod rice, could be a potential natural source for hair growth-promoting products.

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Health Benefits and Safety of Red Pigmented Rice (Oryza Sativa L.): In Vitro, Cellular, and In Vivo Activities for Hair Growth Promoting Treatment

Research cited in this study

research Herbal Preparations for the Treatment of Hair Loss

research Activin B Stimulates Mouse Vibrissae Growth and Regulates Cell Proliferation and Cell Cycle Progression of Hair Matrix Cells through ERK Signaling

research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth

research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum Debile Extract as Functional Food and Nutraceutical Ingredients

research Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies

research Chrysanthemum Zawadskii Extract Induces Hair Growth by Stimulating the Proliferation and Differentiation of Hair Matrix

research In Vivo Hair Growth-Promoting Effect of Rice Bran Extract Prepared by Supercritical Carbon Dioxide Fluid

research Hair Loss and Herbs for Treatment

research 5α-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment

research Investigation of the Topical Application of Procyanidin Oligomers from Apples to Identify Their Potential Use as a Hair-Growing Agent

research The First Clinical Trial of Topical Application of Procyanidin B-2 to Investigate Its Potential as a Hair Growing Agent

research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo

research Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In Vitro and Convert Hair Cycle In Vivo

research Biochemical Analysis of Hair Growth from the Aspects of Aging and Enzyme Activities

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