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research Measurement of cortisol in human Hair as a biomarker of systemic exposure

567 citations , October 2007 in “Clinical and investigative medicine”

This study described a new assay for measuring cortisol in hair and found it may serve as a useful biomarker for long-term cortisol exposure, correlating with 24-hour urine cortisol levels in non-obese subjects.

research Emerging Topical and Systemic JAK Inhibitors in Dermatology

277 citations , December 2019 in “Frontiers in Immunology”

This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.

research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases

263 citations , February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology”

This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.

research Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

260 citations , January 2020 in “Nature”

Stress can cause hair to turn gray by depleting stem cells.

research The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults

213 citations , June 2017 in “Rheumatology”

This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.

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Learn

10 / 39 results

learn Synergen Complex ®

learn sh-Polypeptide-7

Is sh-Polypeptide-7 considered a natural or synthetic ingredient, and how is it typically applied? sh-Polypeptide-7 is a synthetic ingredient applied in hair-care products.

learn Follistatin

Can follistatin be applied topically, or is it only effective through injections or systemic use? Follistatin is not effective when applied topically and requires injections or systemic use.

learn Glycerin

What’s the difference between vegetable glycerin and synthetic glycerin in hair products? Vegetable glycerin is plant-derived, while synthetic glycerin is petroleum-based, but both are chemically identical.

learn Thymosin Beta 4

Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 is primarily being explored as a topical treatment for hair loss.

learn Hair Transplant

Is ARTAS or NeoGraft a better hair transplant procedure? ARTAS offers advanced robotic precision, while NeoGraft is a reliable manual option.

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

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Community Join

5 / 1000+ results

community Non-systemic hair loss stack, is there any hope?

6 upvotes 2 weeks ago

A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

community Minimizing systemic DHT reduction with topicals

5 upvotes 3 weeks ago

The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

community 4 years wearing hair systems - what nobody tells you when you start

227 upvotes 6 months ago

Hair systems require frequent maintenance and can be costly, but a DIY approach with bi-weekly changes can help manage these issues. Minoxidil and finasteride were tried but not consistently used due to side effects and personal preferences.

community From Denial to Acceptance: Hair as Amplifier, Not Foundation – Open to Hair Systems for Freedom

in Hair Systems 9 upvotes 7 months ago

A 24-year-old with early hair loss is managing it with finasteride, minoxidil, and dutasteride, and is considering using a hair system for more styling options while maintaining transparency. They emphasize confidence and self-expression over hair, viewing it as an amplifier rather than a foundation.

community 18m, already balding. Is a hair system the way to go? I don’t have the strength to go bald this young

in Hair Systems 148 upvotes 8 months ago

An 18-year-old with early hair loss is advised to consider minoxidil and finasteride, with a doctor's consultation recommended. Alternatives like a hair system or shaving are suggested due to potential medication side effects and lifelong commitment.

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