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The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

New treatments for male hypogonadism are effective and should be personalized.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

COVID-19 may harm male fertility and damage the reproductive system.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Women with different PCOS types have similar fertility treatment results.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

A group has developed therapies that show promise for treating cancer and various other conditions.

Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Gene mutations can cause problems in male genital development.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.