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Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

New technologies help us better understand how skin microbes affect skin diseases.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Certain genetic differences may affect how likely someone is to get COVID-19 and how severe it might be.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

New treatments for skin and hair disorders in women of color address unique biological differences and include specific acne medications, sunscreens, skin lighteners, and hair care adjustments.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.

CD4+ skin cells may be precursors to basal cell carcinoma.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Essential oils may help hair health but lack strong scientific proof and can cause allergic reactions.

Psoralea corylifolia Linn. is a medicinal plant used for skin diseases and has various health benefits.

Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.