research Leptin Controls Hair Follicle Cycling
Leptin helps start the growth phase of hair.
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research Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo
Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
research Hair Growth Effect of Minoxidil
Minoxidil helps hair grow by improving blood flow and increasing growth factors in hair follicles.
research Genetic and Molecular Aspects of Androgenetic Alopecia
Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.
research Expression of AKT1 Along with AKT2 in Granulosa-Lutein Cells of Hyperandrogenic PCOS Patients
The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
research Tumor Necrosis Factor Alpha, Interferon Gamma, and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin
TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
research Hormone Therapy in Acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro
The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
research The Role of Androgen Therapy
Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
research Relationship Between Betacoronaviruses and the Endocrine System: A New Key to Understand the COVID-19 Pandemic—A Comprehensive Review
Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Endocrinology of the Aging Prostate: Current Concepts
Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.
research Hormonal Therapy in Female Pattern Hair Loss
Hormonal therapies help treat female hair loss, but results are slow and vary.
research CCN2 Modulates Hair Follicle Cycling in Mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research Anti-Androgen Effects of Extracts and Compounds from Ganoderma Lucidum
Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
research Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
research Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research The Endocrinology of Baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Aromatase Inhibitors Induce Male Pattern Hair Loss in Women
Aromatase inhibitors cause male pattern hair loss in women.
research Dopamine Is a Novel, Direct Inducer of Catagen in Human Scalp Hair Follicles In Vitro
Dopamine stops hair growth and pigment production in human scalp hair follicles.
research The Role of Inflammation and Immunity in the Pathogenesis of Androgenetic Alopecia
Inflammation and immunity play a key role in androgenetic alopecia, with better treatment outcomes in certain immune-positive cases.
research Update on the Pathogenesis, Genetics, and Medical Treatment of Patterned Hair Loss
New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.
research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
research Treatment of Androgenic Disorders in Women: Acne, Hirsutism, and Alopecia
Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Lactoferrin Promotes Hair Growth in Mice and Increases Dermal Papilla Cell Proliferation Through Erk/Akt and Wnt Signaling Pathways
Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?
Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.