Estrogen and Progesterone Receptors in Androgenic Alopecia Versus Alopecia Areata

April 1998 in “ American Journal of Dermatopathology ”

Michael B. Wallace, Bruce R. Smoller

androgenic alopecia alopecia areata estrogen receptor progesterone receptor immunohistochemical staining pilosebaceous units mesenchymal cells ER PR

TLDR Estrogen and progesterone don't directly affect hair growth in androgenic alopecia and alopecia areata.

The study conducted 25 years ago compared the immunohistochemical staining characteristics of nine cases of androgenic alopecia with those of 13 cases of alopecia areata using estrogen receptor (ER) and progesterone receptor (PR) markers. The results indicated that estrogen and progesterone receptor expression is not significantly increased or decreased in the pilosebaceous units or surrounding mesenchymal cells in androgenic alopecia vs. alopecia areata. Therefore, it was concluded that an indirectly mediated process of estrogen/progesterone control on hair growth and development must be presumed for cases of androgenic alopecia.

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Research cited in this study

6 / 6 results

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research Estrogen and Progesterone Receptors in Androgenic Alopecia Versus Alopecia Areata

27 citations, April 1998 in “American Journal of Dermatopathology”

Estrogen and progesterone don't directly affect hair growth in androgenic alopecia and alopecia areata.

Estrogen and Progesterone Receptors in Androgenic Alopecia Versus Alopecia Areata

Research cited in this study

research Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia

research Androgens and Human Hair Growth

research Reduced Serum Vitamin B12 Levels During Oral Cyproterone Acetate and Ethinyl Estradiol Therapy in Women With Diffuse Androgen-Dependent Alopecia

research Pregnancy and the Skin

research Physiologic Skin Changes in Pregnancy

research Alopecia: A Pathologist's View

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