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Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Hormones and genes affect hair growth and male baldness.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The Hairless gene is crucial for healthy skin and hair growth.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Sex steroids affect the MafB gene differently in male and female hamsters.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells and their environments are key to skin repair and maintenance.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Different types of skin cells play specific roles in development, healing, and cancer.