8 citations,
January 1996 in “Gynecological Endocrinology” Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
February 2017 in “Vestnik dermatologii i venerologii” Hair loss can be treated with common methods like minoxidil and finasteride, but new potential treatments include growth factors, cytokines, and platelet-rich plasma injections.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
10 citations,
October 1993 in “Archives of dermatological research” Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.
5 citations,
January 1983 in “Australian journal of biological sciences” Certain amino acid analogues can inhibit wool and hair growth and affect fiber strength.
3 citations,
March 2017 in “International journal of women’s dermatology” Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.
42 citations,
August 1999 in “The American journal of pathology” Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
30 citations,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
24 citations,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
48 citations,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
30 citations,
April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
46 citations,
March 2001 in “Journal of endocrinological investigation” 5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
59 citations,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
2 citations,
November 2017 in “PloS one” Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
11 citations,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
40 citations,
October 2002 in “Endocrinology” Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
1 citations,
February 2017 in “MOJ bioequivalence & bioavailability” Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
1 citations,
March 2023 in “Frontiers in Medicine” Topical prostaglandin analogs may help with hair growth but more research is needed.
53 citations,
October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
19 citations,
April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
2 citations,
August 2014 in “Journal of dermatological science” Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.
22 citations,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
218 citations,
April 2012 in “British Journal of Dermatology” Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.
6 citations,
April 2014 in “European journal of medicinal chemistry” New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
28 citations,
September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
98 citations,
April 1997 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively blocks rat enzymes, but with varying methods and strength.
14 citations,
November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.
January 2023 in “Open veterinary journal” Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.