7 citations
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January 2015 in “Biological & Pharmaceutical Bulletin” This study found that a 16-week dermal application of rice bran extract significantly increased hair density and diameter in male androgenic alopecia patients without causing adverse reactions.
1 citations
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November 2023 in “Brain and behavior” This study found that spironolactone improved cognitive performance in patients with bipolar disorder experiencing manic episodes, but did not significantly affect manic symptoms, recommending further research with larger sample sizes and longer follow-ups.
7 citations
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August 2023 in “EClinicalMedicine” This study reported that anti-androgens combined with lifestyle modifications were more effective than metformin and lifestyle in reducing hirsutism and certain hormonal measures in women with PCOS, but they were not more effective than a placebo combined with lifestyle changes.
36 citations
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January 2014 in “Evidence-based Complementary and Alternative Medicine” This study found that men with androgenetic alopecia treated with pumpkin seed oil for 24 weeks experienced a notable 40% increase in hair count compared to a 10% increase with a placebo.
2 citations
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September 2024 in “Journal of Dermatological Treatment” In this study, combining compound glycyrrhizin with topical minoxidil was more effective and as safe as minoxidil alone for treating alopecia areata.
November 2023 in “Journal of Cosmetic Dermatology” This study concluded that while both 5% topical and 1 mg oral minoxidil significantly improved hair diameter in androgenetic alopecia patients, there was no significant difference in overall effectiveness or patient satisfaction between the treatments.
22 citations
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March 2020 in “Journal of The American Academy of Dermatology” This study found that injecting autologous dermal sheath cup cells significantly increased hair density and diameter in male and female pattern hair loss compared to a placebo for up to 9 months.
3 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This review discusses pumpkin seed oil as a potential treatment for androgenetic alopecia but reports no clinical results on its effects on frontal hair loss; it emphasizes the need for further research.
August 2023 in “Skin Research and Technology” In this clinical trial, oral consumption of a persimmon leaf extract-containing complex significantly increased hair density and thickness over 24 weeks compared to a placebo, although improvements in hair gloss were not statistically significant.
December 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-level light therapy significantly increased hair density and thickness in people with hair loss, but they didn't notice a difference.
July 2025 in “Frontiers in Medicine” In this systematic review and meta-analysis, the authors examined single-spin versus double-spin centrifugation protocols for PRP in patients with androgenic alopecia and found no significant difference in platelet concentration, hair density, or hair types between the protocols.
1 citations
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August 2017 in “Journal of food and nutrition research” This study found that the black bean-licorice-biotae folium extract may improve hair diameter, scalp moisture, and sebum secretion, although its effect on hair density was not significant.
1 citations
,
November 2023 in “Journal of Ayurveda and Integrative Medicine” In this study, a topical Ashwagandha serum significantly improved hair growth, density, thickness, and quality of life in adults with mild to moderate hair loss compared to a placebo, demonstrating potential as an effective and safer alternative treatment for alopecia.
25 citations
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February 2014 in “British journal of dermatology/British journal of dermatology, Supplement” The authors concluded that intralesional triamcinolone acetonide may benefit patients with patch-type alopecia areata, but the evidence is limited due to small, bias-prone studies with variations in treatment protocols.
1 citations
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January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This review indicates that low-level laser therapy may stimulate hair growth in both men and women with androgenetic alopecia, showing similar efficacy to minoxidil in some studies, but requires more robust evidence.
41 citations
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September 2018 in “Australasian journal of dermatology” This review suggests that oral prednisolone pulse therapy and oral inosiplex may be effective for alopecia areata, but robust evidence from randomized controlled trials is lacking, highlighting the need for better-designed future studies.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
January 2019 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study suggests that low level laser therapy may be effective for alopecia compared to placebo, but current evidence is limited and studies show a high risk of bias.
June 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This literature review reports that certain herbal remedies, such as rosemary, green tea, and ginseng, have shown promise in promoting hair growth and improving hair density, though variability and study design limitations highlight the need for more rigorous research.
26 citations
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December 2019 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that platelet-rich plasma combined with topical minoxidil was more effective in increasing hair density for male-type baldness than either treatment alone.
2 citations
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March 2024 in “Journal of Cosmetic Dermatology” This study highlighted the need for more extensive research, ideally randomized controlled trials with larger patient groups, to determine the effect of the indicated treatment on hair repigmentation following AA.
February 2025 in “Journal of Caring Sciences” This article emphasizes that the CONSORT statement is a guideline for reporting randomized controlled trials, not a tool for assessing risk of bias.
March 2026 in “Preprints.org” This study reviewed evidence for six minimally invasive treatments for androgenetic alopecia, finding consistent support for platelet-rich plasma and topical finasteride, while other options like microneedling and intradermal dutasteride showed promise but need further and standardized research.
7 citations
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May 2021 in “Frontiers in Pharmacology” This review highlights platelet-rich plasma as a promising nonsurgical treatment for female pattern hair loss, but it reports no new clinical results.
October 2025 in “Journal of Drugs in Dermatology” This study suggests that topical caffeine may be a safe and promising treatment for hair loss, but the researchers highlight the need for more large-scale randomized trials to confirm its efficacy.
This study reviewed two blinded randomized controlled trials and one prospective cohort study and found that PRP injections may increase hair density and induce hair regrowth in adults with androgenic alopecia and alopecia areata, with notably higher hair counts reported at specific follow-up intervals.
60 citations
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December 2015 in “Lasers in Medical Science” This review concluded that FDA-cleared low-level laser therapy devices are safe and effective for patients with male and female pattern hair loss who do not respond to or tolerate standard treatments.
25 citations
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March 2017 in “Journal of Dermatological Treatment” This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.
June 2022 in “Frontiers in Medicine” This review discusses acupuncture and moxibustion for alopecia and reports evidence suggesting their efficacy for various types of hair loss, but notes barriers like cost and aversion to needles.
12 citations
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May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This review found insufficient evidence to determine methotrexate's effectiveness for maintaining regrowth in extensive alopecia areata, and suggests its potential role in inducing regrowth when combined with corticosteroids.