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This case report describes two patients with ulcerative colitis and alopecia areata who did not respond to various treatments but achieved remission and improved hair growth after starting tofacitinib.

This case report documented successful full hair regrowth in an 8-year-old with alopecia universalis after oral tofacitinib treatment, but mild headaches led to discontinuation.

This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.

The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.

In this study, pediatric patients who underwent tissue expansion surgery reported varying quality-of-life outcomes, with a median score of +17, and most would recommend the procedure despite some negative experiences, indicating the need for further research to understand factors influencing these outcomes.

The authors concluded that capecitabine and high-dose toremifene may be an effective treatment option for patients unable to undergo anthracycline or taxane therapies, based on one woman's cancer management.

This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.

Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.

This review found that the DLQI is widely used as a benchmark in the development and validation of dermatology quality-of-life measures.

In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.

QMSI effectively maps and quantifies drug distribution in skin tissues.

This study confirms that zebrafish engineered with Cantú Syndrome mutations in ABCC9 and KCNJ8 genes exhibit gain-of-function characteristics in their cardiovascular KATP channels, similar to mammalian counterparts.

Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.

This study found that tofacitinib and baricitinib, when administered with unorthodox weight-stratified dosing in pediatric patients with moderate-to-severe AA, showed comparable efficacy and tolerability, though baricitinib's efficacy decreased with non-standard dosing.

Topical tofacitinib helped a man with severe scalp condition after other treatments failed.

This study developed a prototype device that suggests potential for diagnosing changes in hair quantity, diameter, and density, though formal clinical studies are needed to confirm these findings.

In this review, researchers summarize the methods for characterizing telocytes, outline their physiological roles and implications in diseases, and discuss potential future studies including precise markers and targeted therapies.

This study evaluated the effectiveness and safety of ritlecitinib in patients aged 12 or older with alopecia totalis or universalis, finding higher hair regrowth response rates compared to placebo at 24 weeks, with continued improvement and acceptable safety through 48 weeks.

This review discusses the shift in toxicity profiles of cancer therapies from traditional chemotherapy to targeted agents, noting similar overall toxicities but with different side effects, and reports no new findings.

This review discusses the progress and challenges of targeted protein degradation therapies, highlighting the increasing number of degraders in cancer clinical trials and the limited diversity in targeted proteins, primarily focusing on those employing CRL4^CRBN as the E3 ligase.

Trichoscopy helped diagnose and treat a child's fungal scalp infection by spotting specific hair shapes.

In this retrospective study, combining TACE with Donafenib showed promising results as a first-line treatment for Chinese patients with unresectable hepatocellular carcinoma, yielding a median progression-free survival of 12.8 months and a one-year overall survival rate of 87.5%, along with a favorable safety profile.

This study validated a UV-spectrophotometric method for accurately detecting Minoxidil and Tofacitinib citrate concentrations in bulk and gel formulations for alopecia areata, showing high recovery rates and indicating the method's suitability for routine analysis.

This review revisits hair-thread tourniquet syndrome, highlighting the importance of prompt diagnosis and treatment by removing the constricting hair or similar substance to prevent damage to affected body parts, aiming to raise healthcare professionals' awareness for better prevention and management.

In a study on secondary hair follicle stem cells from Arbas cashmere goats, researchers found that 10 μg/mL quercetin for 48 hours enhances cell proliferation and inhibits apoptosis through multiple signaling pathways, potentially improving cashmere production.

This review discusses systemic antifungal treatments for tinea capitis in children, noting that newer agents like terbinafine and itraconazole require shorter courses than the traditional griseofulvin, but may be more costly.

In this study, researchers assessed the stability of various formulations in the TrichoConcept™ line for customized alopecia treatment. They found that the combinations remained stable from 14 to 180 days, supporting the use of these vehicles for enhancing therapeutic outcomes in hair loss treatments.

In human hair follicle keratinocytes, this study found that treatment with the pharmacological inhibitor QLT0267 led to a strong inhibition of proliferation and migration and induced nearly 100% apoptosis.