October 2022 in “Biomedicines” The review investigates the transgenerational effects of finasteride-induced androgen imbalance on endoplasmic reticulum (ER) stress, oxidative stress, and liver disorders. It was found that finasteride treatment in male rats led to significant metabolic and cellular stress in their offspring, including hyperglycemia and increased hepatic glycogen accumulation. The study highlights the role of androgen receptors in regulating ER stress and the unfolded protein response (UPR) in the liver, suggesting that these mechanisms could be potential therapeutic targets for liver diseases. The findings emphasize the need for further research into how finasteride and similar drugs may induce hereditary changes affecting offspring health.
October 2022 in “Frontiers in Bioengineering and Biotechnology” This study investigates bioengineered polyester nanoparticles (NPs) coated with dermal papilla cell membranes for treating androgenic alopecia (AGA). These NPs encapsulate dutasteride (DUT) and siRNA targeting the androgen receptor (siAR), aiming to suppress 5α-reductase and knockdown androgen receptors. The cell membrane coating enhances biocompatibility and targeted drug delivery to hair follicles. In vitro and in vivo experiments showed that these NPs effectively penetrated skin, released drugs in a controlled manner, and significantly promoted hair growth in a mouse model, suggesting a promising therapeutic approach for AGA.
August 2022 in “International Journal of Molecular Sciences” 7 citations,
June 2021 in “Amino acids” Human hair protein modifications could potentially indicate heart disease risk.
15 citations,
June 2014 in “Integrative cancer therapies” Pranic meditation significantly improved mental health and quality of life for breast cancer survivors.
Chinese and Japanese bloggers discuss different topics and have varying opinions, reflecting cultural differences.
Kalya Research is an AI tool that effectively finds and analyzes alternative medicine literature, saving researchers time.
January 2019 in “Research Square (Research Square)” The trial will test if YH0618 granule prevents hair loss in breast cancer patients during chemotherapy.
January 2023 in “Psychology” Emotional Freedom Techniques (EFT) treatment improved seed germination and growth, suggesting mood affects seed viability.
January 2021 in “Annals of translational medicine” YH0618 helped reduce skin and nail problems and fatigue in chemotherapy patients.
4 citations,
May 2020 in “Annals of palliative medicine” Plum blossom needle acupuncture with qi-invigorating therapy is more effective for Seborrheic Alopecia than Western medicine.
Renshen Yangrong Tang is effective for treating various disorders linked to qi and blood deficiency.
4 citations,
May 2022 in “Medicina” Kampo medicine can help treat general fatigue from long COVID.
3 citations,
May 2013 in “PubMed” Research on Hutchinson-Gilford progeria syndrome could help understand normal aging and heart disease.
August 2024 in “Journal of Contemporary Medical Practice” Professor Ma Shuanquan treats hair loss by using Chinese medicine to improve liver, spleen, and kidney health.
January 2022 in “Kampo Medicine” Ninjin'yoeito, a Japanese medicine, helped stop hair loss and improved mood in two post-COVID-19 patients.
Using a combination of AMD3100 and FK506 can speed up and improve wound healing in diabetic rats.
1 citations,
October 2023 in “Journal of the American Academy of Dermatology” The document concludes that improving patient safety and quality is increasingly important in dermatology.
71 citations,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
59 citations,
May 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
55 citations,
June 2014 in “Nature Communications” Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
49 citations,
March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
47 citations,
April 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
36 citations,
January 2017 in “Stem Cells International” A special stem cell fluid can speed up wound healing and hair growth in mice.
25 citations,
May 2020 in “Progress in Organic Coatings” Castor oil-based polyurethanes are promising for making safe, strong-performing, eco-friendly hair-styling products.
24 citations,
January 2019 in “Science China Life Sciences” Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
23 citations,
December 2013 in “Molecular cancer therapeutics” Breast cancer treatments work better with AR activation, improving results and reducing side effects.
17 citations,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
15 citations,
May 2022 in “Journal of Infection” COVID-19 vaccines are safe and highly effective for children, with inactivated vaccines being slightly better.