53 citations
,
January 1993 in “Biochemical Pharmacology” This study reports a method for efficiently synthesizing chromeno-pyrimidine-N-oxides in good to excellent yields, confirmed by X-ray analysis, through a reaction between 4-chloro-3-formylcoumarin and aromatic carboximide oximes.
January 1987 in “Data Archiving and Networked Services (DANS)” This article discusses the metabolism of benzo(a)pyrene in chemical carcinogenesis and reports no new experimental findings.
2 citations
,
August 2019 in “Turkish Journal of Chemistry” This study reported that CoFe2O4 magnetic nanoparticles efficiently catalyzed the synthesis of minoxidil from 2,6-diamino-4-chloro-pyrimidine N-oxide, achieving a 95% yield with sustained reusability.
October 2025 in “Frontiers in Endocrinology” This study confirmed that methimazole use is associated with agranulocytosis, pyrexia, exposure during pregnancy, and hyperthyroidism, while also identifying new safety signals like premature birth and septic shock that require further investigation.
This study identified that α-ketobutyrate (α-KB) extends lifespan and improves health markers in Caenorhabditis elegans and aged mice by modulating pyruvate metabolism and activating AMPK pathways, with potential implications for human anti-aging treatments.
7 citations
,
May 2016 in “European Polymer Journal” This study found that biodegradable hyperbranched polyesters improved the solubility and loading capacity of hydrophobic drugs, with complete pyrene release achieved in 16 days under enzymatic conditions.
January 2021 in “ABC Heart Failure & Cardiomyopathy” This case report describes a 90-year-old man diagnosed with wild-type transthyretin cardiac amyloidosis, confirmed by pyrophosphate cardiac scintigraphy and exclusion of gene mutations.
2 citations
,
September 2000 in “International Journal of Retail & Distribution Management” This issue reviews various reports on branding, including UK consumer attitudes towards brand extensions and company performance in 1999, but provides no new research findings.
97 citations
,
December 2010 in “Journal of Neuroscience” This study found that midazolam, unlike clonazepam, increased neurosteroid levels and affected synaptic inhibition and plasticity in rat hippocampal neurons, suggesting unique actions via dual receptor activation.
12 citations
,
February 2011 in “Equine veterinary education” This case report describes the clinical and diagnostic features of a mare with mammary lymphoma associated with anaemia and pruritus.
11 citations
,
February 2002 in “European Journal of Clinical Investigation” This study found that two new platinum complexes significantly extended survival in rats with induced tumors, showing effective antitumor activity without severe toxicity.
5 citations
,
October 2001 in “British Journal of Ophthalmology” This abstract describes the initial success of intralesional cidofovir for SCC treatment and states that it has not shown systemic toxicity, but it does not report new clinical trial results.
1 citations
,
October 2017 in “Food Additives & Contaminants: Part A” This study identified a new minoxidil analogue called triaminodil in an illegal hair-growth supplement, but no data on its chemical, toxicological, or pharmacological properties are available yet.
August 2025 in “Journal of Cosmetic Dermatology” In this bibliometric analysis, researchers found an increasing focus on innovative treatments for androgenetic alopecia, such as platelet-rich plasma and stem cell therapy, with the United States and China leading in research contributions between 2003 and 2023.
346 citations
,
April 2020 in “Frontiers in Oncology” This review discusses the roles of key epithelial-mesenchymal transition factors and potential therapeutic opportunities involving cancer metabolic pathways, reporting no new clinical results.
111 citations
,
February 2017 in “Antiviral research” In this study, researchers discovered that several compounds, including brequinar and 6-azauridine, exhibit significant anti-Zika virus activity using a high-throughput screen assay.
86 citations
,
February 2009 in “Journal of Neuroscience” This study found that during late pregnancy in rats, there is an increase in extrasynaptic GABA A receptor number in granule cells of the dentate gyrus, linked to hormonal fluctuations.
33 citations
,
March 2018 in “Trends in cell biology” This review summarizes evidence suggesting that metabolism actively influences stem cell fate in intestinal and hair follicle stem cells, rather than being a mere environmental byproduct.
31 citations
,
December 1997 in “Developmental Medicine & Child Neurology” This case report describes a 5-year-old girl with biotinidase deficiency who had acute visual loss and gait disturbance but no typical symptoms, responding well to biotin therapy.
21 citations
,
April 2021 in “Biofabrication” This study developed a vascularized full-thickness skin equivalent with a complex vascular network, enhancing its predictiveness for topical and systemic drug applications in dermatology research.
11 citations
,
March 2019 in “Journal of Medicinal Chemistry” This study reports that synthetic carbohydrate receptors effectively inhibit Zika virus infection in cell cultures by blocking early stages of viral entry.
8 citations
,
March 2019 in “Drugs - Real World Outcomes” This study reported that while general patient characteristics and adverse event incidence for eribulin were comparable between a healthcare claims database and post-marketing surveillance, significant differences in some side effects such as neutropenia were observed.
7 citations
,
October 2020 in “Science and Innovations in Medicine” This review discusses how fibroblast metabolic processes and life span are influenced by the malate dehydrogenase shuttle system and highlights factors affecting fibroblast proliferative activity, without presenting new experimental results.
6 citations
,
March 2022 in “Frontiers in drug discovery” This review summarizes 25 small molecule drugs with in vitro and in vivo data for COVID-19 treatment, highlighting their structural diversity and potential to guide future antiviral discovery.
5 citations
,
January 2024 in “Fermentation” This study found that fermenting porcine and equine placentas with a specific lactic acid bacterial strain enhanced the moisturizing abilities and cell proliferation properties compared to traditional placental extracts, suggesting their potential for cosmetic applications.
4 citations
,
May 2021 in “Research Journal of Science and Technology” This review discusses the therapeutic applications of Hibiscus rosa sinensis and reports no new clinical results; the authors highlight its potential in herbal medicine.
2 citations
,
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study demonstrated that ablation of individual somatostatin-expressing interneurons increased activity in nearby neurons of the mouse motor cortex during motor learning.
July 2026 in “IntechOpen eBooks” This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.
June 2026 in “Expert Opinion on Pharmacotherapy” This article reviews emerging therapies for androgenetic alopecia, highlighting advances like androgen-receptor antagonists and improved minoxidil delivery that aim to enhance treatment efficacy and safety.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review summarizes the medicinal properties and bioactive compounds of Hibiscus rosa sinensis, highlighting its various pharmacological uses such as analgesic, anti-inflammatory, and anti-depressant effects based on previous studies conducted on this plant.